The origin of a common compound about Ethyl 2-(4-chloro-2-(methylthio)pyrimidin-5-yl)acetate

According to the analysis of related databases, 61727-34-2, the application of this compound in the production field has become more and more popular.

Application of 61727-34-2, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 61727-34-2, name is Ethyl 2-(4-chloro-2-(methylthio)pyrimidin-5-yl)acetate. This compound has unique chemical properties. The synthetic route is as follows.

To a solution of 121 (2.6 g, 10 mrnoi) in EtOH (20 mL) is added zinc powder (2.6 g, 40 mrnol) and HOAc (2 mL). After stirring at room temperature overnight, the mixture is filtered and concentrated. The residue is dissolved in EA (30 mL), washed with brine, diied over anhydrous sodium sulfate, filtered, and concentrated to give 122 as a yellow oil (1,2 g, 56% yield). (MS: [M+H] 213.1)

According to the analysis of related databases, 61727-34-2, the application of this compound in the production field has become more and more popular.

Reference:
Patent; IMMUNE SENSOR, LLC; THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM; ZHONG, Boyu; SUN, Lijun; SHI, Heping; LI, Jing; CHEN, Chuo; CHEN, Zhijian; (270 pag.)WO2017/176812; (2017); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia