On July 7, 1982, Takagishi, Yasushi; Ohsuga, Kiichiro; Ohama, Sadao published a patent.Recommanded Product: 23256-42-0 The title of the patent was Suppositories containing trimethoprim/sulfamethoxazole and a phospholipid. And the patent contained the following:
Antimicrobial pharmaceutical or veterinary compositions suitable for colonic administration comprise sulfamethoxazole-trimethoprim (I-II mixture) [8064-90-2] or their salts as the active ingredients and a phospholipid (0.5-5% by weight) for the purpose of preventing the solidification at the step of mixing I and II with a base material(s) and for solving simultaneously the delay of disintegration. Thus, a suppository containing I 20, II 4, phospholipid (soya lecithin) 2, and Witepsol 74 parts disintegrated after storage at cold and room temperature for 3 mo in 9 and 13 min, resp., compared to 35 min and not even after 60 min, resp., for controls. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Recommanded Product: 23256-42-0
The Article related to antimicrobial sulfamethoxazole trimethoprim phospholipid, veterinary sulfamethoxazole trimethoprim phospholipid, lecithin sulfamethoxazole trimethoprim suppository, Pharmaceuticals: Formulation and Compounding and other aspects.Recommanded Product: 23256-42-0
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia