Tag: 300-400

On February 24, 2010, Xu, Kefu published a patent.Name: 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate The title of the patent was Medical composition for treating chicken necrotizing enterocolitis and its preparation. And the patent contained the following:

The title medical composition contains apramycin sulfate 2-10, sulfamethoxydiazine sodium 2-15, trimethoprim lactate 0.4-3, atropine sulfate 0.1-0.5%, and tannic acid. The preparation method comprises pulverizing and screening raw materials, weighing, and sufficiently mixing for 1h to obtain. This inventive composition can be used for treating chicken necrotizing enterocolitis. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Name: 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

The Article related to chicken necrotizing enterocolitis apramycin sulfamethoxydiazine trimethoprim lactate atropine tannate, trimethoprim lactate atropine sulfate tannic acid, Pharmacology: Effects Of Gastrointestinal and Respiratory Drugs and other aspects.Name: 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On June 24, 2015, Dai, Liang published a patent.Formula: C17H24N4O6 The title of the patent was Boron carbide filling-modified plastic and preparation method thereof. And the patent contained the following:

Title plastic is composed of LDPE 100, nano antimony tin oxide 4.5-6.8, nano titanium dioxide 1-2, epoxy soybean oil 2-3, stalk ashes 1-3, nano silica 0.4-0.8, trimethoprim lactate 0.1-0.3, barium chromate 0.2-0.4, boron carbide 0.4-0.5, maleic anhydride grafted compatibilizer 1.2-1.6 weight parts, and appropriate amount of dehydrated alc. Title method includes the following steps: calcining nano antimony tin oxide and nano titanium dioxide at 620-810°C for 30-50 min, cooling, placing in a three-neck flask, adding anhydrous ethanol and maleic anhydride grafted compatibilizer, stirring evenly, and heating at reflux for 4-5 h, centrifuging, washing with anhydrous ethanol for 2-3 times, and vacuum drying at 80°C; adding stalk ashes and nano silica to the above product, and mixing evenly to prepare mixed powder; adding low-d. polyethylene to the high-speed mixing and dispersing machine, adding the mixed powder, boron carbide and other remaining ingredients, mixing and dispersing for 15-20 min, pouring into a twin-screw extruder, extruding and granulating. The prepared plastic has improved wear resistance, good heat stability, UV irradiation resistance, aging resistance, high intensity and chem. resistant properties, is deeply processed into plastic film used for green house of vegetables, has short degradation cycle, strong lower temperature resistance, obvious effect of heat insulation, self-cleaning and antibacterial property, and high transmittance. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Formula: C17H24N4O6

The Article related to ldpe oxide epoxy soybean oil trimethoprim lactate, Plastics Manufacture and Processing: Formulating Procedures and Compositions and other aspects.Formula: C17H24N4O6

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On March 25, 2015, Fei, Xianchao published a patent.Computed Properties of 23256-42-0 The title of the patent was One kind of plastic-rubber composite sheet. And the patent contained the following:

The present invention discloses a plastic-rubber composite sheet material, characterized in that it is composed of the following parts by weight of raw materials: high-d. polypropylene 102-110, dihydrated gypsum powder 3-5, benzalkonium bromide 0. 2-0. 4, anhydrous calcium chloride 2-3, di-sec-octyl phthalate 2-4, table salt 0. 4-1, precipitated silica 5-8, calcium ricinoleate 2-3, trimethoprim lactate 0. 4-1, hexafluoroacetylacetone 0. 3-1, illite powder 6-9, polyurethane 1-2, ammonium chloride 0. 2-1, non-woven fabric crushing materials 6-10, thermoplastic styrene-butadiene rubber 2-4, divinylbenzene 1-2, and anticorrosive additive 1-2 weight parts. The anticorrosive additive is composed of polymethyl methacrylate 30-40, diacetone acrylamide 0.3-1, Et silicate 1-2, Ca propionate 3-5, dihydroacetic acid 2-3, ammonium metavanadate 0.8-1, anhydrous ethanol 4-6 and lauryl di-Me amine oxide 0.3-1 weight parts. The anticorrosive additive is prepared by adding Et silicate into anhydrous ethanol, stirring uniformly to obtain the alc. ester solution; mixing dihydroacetic acid and Ca propionate, ball milling uniformly, adding into deionized water, stirring uniformly, adding lauryl di-Me amine oxide, stirring uniformly to obtain the dispersion solution; heating the polymethyl methacrylate to 100-105°C, adding alc. ester solution, stirring uniformly, adding diacetone acrylamide, keeping the temperature and stirring for 1-2 h, adding dispersion solution, stirring and mixing at 200-300 r/min for 10-20 min, adding the left raw materials, completely stirring and dewatering, and drying at 70-80°C for 3-5 min to obtain the anticorrosive additive. The preparation method of the plastic-rubber composite sheet includes preheating thermoplastic styrene-butadiene rubber and non-woven fabric crushing materials at 110-115°C for 10-20 min, adding di-sec-octyl phthalate, stirring to 50-60°C to obtain esterification material, keeping the temperature; mixing anhydrous calcium chloride and calcium ricinoleate, stirring uniformly, adding polyurethane, stirring and mixing at 60-70°C for 6-10 min, adding the above esterification material, completely mixing, adding table salt, melting, extruding, cooling, grinding into powder; mixing the powder and left raw materials, extruding and molding by the sheet extruder. The sheet of the present invention has high elongation at break and tensile strength, readily available raw materials, low cost, simple technique, no three wastes emission during production, and can effectively promote the compatibility between materials and improve product stability and mech. properties by adding SBR. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Computed Properties of 23256-42-0

The Article related to polypropylene butadiene styrene rubber composite, Plastics Manufacture and Processing: Formulating Procedures and Compositions and other aspects.Computed Properties of 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On November 11, 2015, Liang, Ruiyong; Gao, Hai published a patent.COA of Formula: C17H24N4O6 The title of the patent was An aqueous environmentally-friendly abrasion resistant coating. And the patent contained the following:

The title coating is prepared from alkyd resin 90-100, 1, 2- dimethoxyethane 1-2, aluminum borate whisker 3-5, volcanic ash 1-2, expanded perlite 3-4, polyvinyl alc. 2-3, dimethylaminopropylamine 0. 6-1, calcium naphthenate 0. 5-1, isooctyl methacrylate 2-4, magnesium stearate 1-3, manganese sulfate 0. 5-1, aluminum sulfate 1-2, stearic acid 0. 7-1, wollastonite powder 8-12, flame retardant additive 2-4, STPP 1-2, and deionized water 80-100 weight parts. The title coating is produced by mixing volcanic ash, expanded perlite and wollastonite powder, ball milling uniformly to obtain the grinding material; adding STPP into water, stirring uniformly, adding stearic acid and calcium naphthenate, stirring at 30-40 °C for 5-7 min to obtain the activation solution; adding the grinding material into the activation solution, stirring uniformly, adding dimethylaminopropylamine, stirring and dispersing at 100-200 rpm for 20-30 min to obtain the pre-mixture; mixing polyvinyl alc., Mn sulfate and Al sulfate, stirring and mixing at 50-60 °C for 3-5 min, adding above pre-mixture, stirring uniformly, adding 1,2-dimethoxyethane, the left deionized water and alkyd resin, stirring and dispersing at 300-400 rpm for 1-2 h, mixing with the left raw materials, stirring and dispersing at 600-1000 rpm for 20-30 min to obtain the title coating product. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).COA of Formula: C17H24N4O6

The Article related to alkyd resin abrasion resistant coating, Coatings, Inks, and Related Products: Polyester and Alkyd Resin Coatings and other aspects.COA of Formula: C17H24N4O6

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Stone, K. John published an article in 1976, the title of the article was The role of tetrahydrofolate dehydrogenase in the hepatic supply of tetrahydrobiopterin in rats.Formula: C17H24N4O6 And the article contains the following content:

The reduction of 7,8-dihydrobiopterin (I) to 5,6,7,8-tetrahydrobiopterin by tetrahydrofolate dehydrogenase (EC 1.5.1.3) purified from rat liver was competitively inhibited by trimethoprim lactate (II) (0.36-50.mu.M, Ki 0.285.mu.M). The apparent Km for I was 430 times higher than that for dihydrofolate; reduction of I is thus more susceptible to inhibition by II than is dihydrofolate. I.p. administration of II had no effect on the hepatic supply of tetrahydrobiopterin in rats. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Formula: C17H24N4O6

The Article related to liver tetrahydrofolate dehydrogenase tetrahydrobiopterin, trimethoprim liver tetrahydrofolate dehydrogenase, Enzymes: Substrates-Cofactors-Inhibitors-Activators-Coenzymes-Products and other aspects.Formula: C17H24N4O6

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On November 11, 1987, Jooji, Eru Euansu; Debora, Eru Deuookusu published a patent.Application In Synthesis of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate The title of the patent was Pathogenic Neisseria-specific growth medium and its use in clinical diagnosis. And the patent contained the following:

A medium containing vancomycin (I) and lincomycin (II) for selectively growing Neisseria is prepared Its use in clin. diagnosis of pathogenic Neisseria such as N. gonorrhoeae or N. meningitidis is also disclosed. An agar medium containing GC agar base 36.0, Hb 10.0 g/L, Isovitalex enrichment 10.0 mL/L, I 2.0 mg/L, II 1.0, colistin sulfate 7.5, trimethoprim 5.0, amphotericin B 5.0 μg/L, and nystatin 1250 units/L was prepared and tested for its selectivity. The growth of N. gonorrhoeae and N. meningitidis was excellent while growth of other microorganisms such as yeast was inhibited. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Application In Synthesis of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

The Article related to neiserria pathogen selection culture medium, vancomycin lincomycin neiserria pathogen selection, Fermentation and Bioindustrial Chemistry: Methods (Including Analysis) and other aspects.Application In Synthesis of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On December 24, 2014, Wang, Heshan published a patent.Application of 23256-42-0 The title of the patent was Coating material containing white ointment and manufacture method. And the patent contained the following:

Title coating material is manufactured from white ointment 1-2, trimethoprim lactate 0.5-1, tetrabutylammonium bromide 1-2, sodium carbonate 2-3, allyl poly(ethylene glycol) 1-2, celestite powder 6-10, precipitated silica 5-8, dibutyltin dilaurate 0.8-1, polyacrylamide 0.8-1, styrene 120-160, Me acrylate 80-100, Bu methacrylate 40-60, ammonium peroxydisulfate 3-4, OP-10 6-8, bonding additive 5-7, and deionized water 500-600 weight parts. The bonding additive is manufactured from isobornyl acrylate 6-8, acrylic-silicone emulsion 25-30, microcapsule rose essential oil 2-3, dimethylaminoethyl methacrylate 4-6, potassium persulfate 1-2, redwood powder 2-3, poly(N-vinylpyrrolidone) 0.6-1, and deionized water 10-16 weight parts. The invention also provides methods for manufacturing the title coating material and the bonding additive. The white ointment in the title coating material effectively improves compatibility among the materials, promotes uniform and leveling of coating film, and improves film-forming effect and adhesion. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Application of 23256-42-0

The Article related to coating white ointment manufacture, Coatings, Inks, and Related Products: Acrylic and Water-Sol (Electrophoretic) Resin Coatings and other aspects.Application of 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On March 6, 2018, Yu, Haobo; He, Yang; Chen, Changfeng; Yu, Yanzhao; Jiang, Ruijing published a patent.HPLC of Formula: 23256-42-0 The title of the patent was Preparation method of antibacterial corrosion inhibitor for oil field water treatment system. And the patent contained the following:

The title antibacterial corrosion inhibitor is prepared from (by weight) dodecyldimethylbenzylammonium halide (dodecyldimethylbenzylammonium chloride and/or dodecyldimethylbenzylammonium bromide) 5-60%, antibacterial synergistic agent (trimethoprim and/or trimethoprim lactate) 0.5-5%, surfactant (nonyl phenol polyoxyethylene ether and/or octyl phenol polyoxyethylene ether) 10-30%, buffer (sodium hydrogen phosphate and/or sodium dihydrogen phosphate) 3-10% and water in balance by mixing. The antibacterial corrosion inhibitor has high sterilization efficiency to sulfate reducing bacteria (SRB) and saprophytic bacteria (TGB), and has the advantages of long-acting drug effect, no drug resistance, simple production process and low cost as well as good corrosion inhibition effect on CO2 corrosion. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).HPLC of Formula: 23256-42-0

The Article related to oil field water treatment system antibacterial corrosion inhibitor, Fossil Fuels, Derivatives, and Related Products: Lubricants and Functional Fluids and other aspects.HPLC of Formula: 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On July 8, 2015, Wang, Guidong; Song, Rui published a patent.SDS of cas: 23256-42-0 The title of the patent was A kind of composite saponification cutting fluid. And the patent contained the following:

The invention discloses a kind of composite saponification cutting fluid, which is made up of the following raw materials by weight parts: oleic acid 2-3, trimethoprim lactate 0.1-0.2, Na myristate 3-5, p-nitrophenol 0.2-0.4, castor oil polyoxyethylene ether 0.1-0.2, KOH 0.3-0.5, glyceryl carboxylate 0.2-0.3, polyethylene glycol diglycidyl ether 5-7, raw silk 10-13, polymaleic anhydride 10-16, Span 80 0.8-2, and deionized H2O 170-200. The preparation method includes the following steps: (1) adding raw silk to 0.4-0.6% Na carbonate solution, soaking at 98-100° for 60-80 min, filtrating, drying, mixing with trimethoprim lactate, grinding, adding Span-80, deionized H2O, stirring, adding polyethylene glycol diglycidyl ether, mixing and ultrasonic treating for 30-35 min, obtaining fibroin emulsion; (2) taking KOH, adding deionized H2O, stirring, adding oleic acid, heating to 70-80°C, adding Na myristate and p-nitrophenol, insulating and reacting for 30-40 min, obtaining composite saponification liquid; (3) mixing the fibroin emulsion with polymaleic anhydride, standing at 65-70°C for 30-40 min, adding composite saponification liquid, stirring for 10-16 min, obtaining antirust blended emulsion; (4) mixing the antirust blended emulsion with the residual raw materials, stirring for 20-30 min, obtaining cutting fluid. The composite saponification liquor added in cutting fluid of the present invention has excellent extreme pressure and antiwear behavior, can provide long lasting abrasion and corrosion protection. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).SDS of cas: 23256-42-0

The Article related to composite saponification cutting fluid lubricating oil additive, Fossil Fuels, Derivatives, and Related Products: Lubricants and Functional Fluids and other aspects.SDS of cas: 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On January 7, 2015, Sun, Jufu; Dai, Yujun; Zhu, Penxin published a patent.Computed Properties of 23256-42-0 The title of the patent was Antibacterial anticorrosive coatings. And the patent contained the following:

The coatings contain trimethoprim lactate 0.7-1, polyoxymethylene 2-3, ammonium polyphosphate 2-3, turpentine 0.6-1, illite powders 6-8, β-hydroxyalkyl amides 1-2, 2-bromo-4-methylphenol 1-2, precipitated silica 6-10, crosslinking agent TAC 0.5-1, diisocyanates 0.4-1, styrene 140-200, epoxidized soybean oil 2-3, deionized water 500-600, isooctyl acrylate 140-200, sodium persulfate 3-6, OP-10 5-7, and bonding aids 4-5 parts. The bonding aids are prepared from alumina sol, ammonium aluminum sulfate, lanolin, polyethylene glycol dimethacrylate, anhydrous ethanol, isooctyl acrylate, potassium sulfate, OP-10, rosewood micropowders, and deionized water. The coatings have good adhesion and weather resistance. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Computed Properties of 23256-42-0

The Article related to antibacterial anticorrosive acrylate coating weather resistance, Coatings, Inks, and Related Products: Acrylic and Water-Sol (Electrophoretic) Resin Coatings and other aspects.Computed Properties of 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia