Tag: 200-300

Synthesis, antioxidant, and antiviral properties of pyrimidinylsulfamoyl azolyl acetamides was written by Divya, Kuppi Reddy Gari;Sowmya, Donthamsetty V.;Durgamma, Suram;Tharanath, Vadlamudi;Gopal, Divi Venkataramana Sai;Kumar, Malaka Venkateshwarulu Jyothi;Appa Rao, Chippada;Padmaja, Adivireddy;Padmavathi, Venkatapuram. And the article was included in Medicinal Chemistry Research in 2017.Recommanded Product: 40230-24-8 This article mentions the following:

A new class of pyrimidinylsulfamoyl azolyl acetamides was prepared from 2-pyrimidinylsulfamoyl acetic acid and 2-aminoazoles. The methoxy substituted pyrimidinylsulfamoyl oxazolyl acetamide (8e) displayed moderate antioxidant activity. The Me and methoxy substituted pyrimidinylsulfamoyl oxazolyl acetamides (8b, 8e) exhibited antiviral activity on BHK 21 cell lines with IC₅₀ 63.5, 44.5 μg/mL, resp. The compound 8e inhibited cytopathic changes induced by Blue Tongue Virus in cell lines. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8Recommanded Product: 40230-24-8).

4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. Pyrimidine also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.Recommanded Product: 40230-24-8

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Exposure to antibiotics and precocious puberty in children: A school-based cross-sectional study in China was written by Hu, Yabin;Li, Juan;Yuan, Tao;Yu, Tingting;Chen, Yao;Kong, Huijun;Lin, Cuilan;Shen, Zhemin;Tian, Ying;Tong, Shilu;Yu, Xiaodan;Liu, Shijian. And the article was included in Environmental Research in 2022.Reference of 1220-83-3 This article mentions the following:

Foods and water can be contaminated with antibiotics in China, which may affect children′s health, but evidence on antibiotic exposure with precocious puberty (PP) is limited. This study explored the association of antibiotic exposure with PP in a school-based setting. A cross-sectional study with multistage stratified cluster random sampling was conducted in Zhongshan City, Guangdong Province and Qufu City, Shandong Province in China from Oct. 11 to Dec. 5, 2019. A first-morning urine sample was collected to detect antibiotic exposure. We detected 33 of 45 types of antibiotics from eight categories in 928 primary school children aged 6-12 years using HPLS-MS/MS. Detection rate of antibiotics was stratified by sex, study site, and BMI. The Tanner stages were assessed by professional pediatricians from local hospitals. PP is defined as the onset of secondary characters before 8-yr-old or menarche before 10-yr-old for girls and before 9-yr-old for boys. Multivariable logistic regression was performed to examine the association between antibiotic exposure and PP after adjusting potential confounders. The overall detection rate of antibiotics was 93.0% in 928 children. We found the detection rate of tetracyclines and fluoroquinolones in children with PP was significantly higher than that of children with normal puberty (41.4% vs 29.9%, 56.8% vs 50.6%, resp., all p < 0.05). Both fluoroquinolones (odds ratio (OR): 1.835, 95% confidence interval (CI): 1.066-3.158) and tetracyclines (OR: 2.120, 95% CI: 1.175-3.825) were associated with increased OR of PP after adjusting sex, age, BMI, study site, and family income. Specifically, compared to the values less than the limits of detection, low concentration of ofloxacin from fluoroquinolones (OR: 2.056, 95% CI: 1.091-3.875) and high concentration of chlortetracycline (OR: 3.027, 95% CI: 1.126-8.140) and tetracycline from tetracyclines (OR: 2.756, 95% CI: 1.167-6.506) were associated with increased OR of PP. Exposure to antibiotics, especially fluoroquinolones and tetracyclines was pos. associated with precocious puberty. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3Reference of 1220-83-3).

4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3) belongs to pyrimidine derivatives. Pyrimidine also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. Therapy for fungal infections is based mainly on four classes of antifungals: azoles, echinocandins, polyenes, and pyrimidine analogs.Reference of 1220-83-3

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Pyrimidine derivatives as potent and selective A₃ adenosine receptor antagonists was written by Yaziji, Vicente;Rodriguez, David;Gutierrez-de-Teran, Hugo;Coelho, Alberto;Caamano, Olga;Garcia-Mera, Xerardo;Brea, Jose;Loza, Maria Isabel;Cadavid, Maria Isabel;Sotelo, Eddy. And the article was included in Journal of Medicinal Chemistry in 2011.Formula: C16H13N3 This article mentions the following:

Two regioisomeric series of diaryl 2- or 4-amidopyrimidines e. g. I, II have been synthesized and their adenosine receptor affinities were determined in radioligand binding assays at the four human adenosine receptors (hARs). Some of the ligands prepared herein exhibit remarkable affinities (K_i < 10 nm) and, most noticeably, the absence of activity at the A₁, A_2A, and A_2B receptors. The structural determinants that support the affinity and selectivity profiles of the series were highlighted through an integrated computational approach, combining a 3D-QSAR model built on the second generation of GRid Independent Descriptors (GRIND2) with a novel homol. model of the hA₃ receptor. The robustness of the computational model was subsequently evaluated by the design of new derivatives exploring the alkyl substituent of the exocyclic amide group. The synthesis and evaluation of the novel compounds validated the predictive power of the model, exhibiting excellent agreement between predicted and exptl. activities. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8Formula: C16H13N3).

4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. The pyrimidine derivatives can easily interact with enzymes, genetic materials, and bio components within the cell. Pyrimidine derivatives also play an important role in drug development, either in concert with other compounds or on their own.Formula: C16H13N3

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Highly enhanced biodegradation of pharmaceutical and personal care products in a novel tidal flow constructed wetland with baffle and plants was written by Cheng, Yu-Xiao;Chen, Jun;Wu, Dan;Liu, You-Sheng;Yang, Yong-Qiang;He, Lu-Xi;Ye, Pu;Zhao, Jian-Liang;Liu, Shuang-Shuang;Yang, Bin;Ying, Guang-Guo. And the article was included in Water Research in 2021.Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide This article mentions the following:

Research on decentralized wastewaters deserves special focus due to the potential abundance of emerging organic pollutants including pharmaceutical and personal care products (PPCPs), which might pose serious threats to the local water bodies and even to human health. Constructed wetland (CW) is a common decentralized wastewater treatment technol., with a certain ability to eliminate PPCPs. Nonetheless, PPCPs removal in common CWs is frequently challenging, besides, the removal mechanism remains elusive. Based on our previous study, tidal flow constructed wetlands (TFCWs) is effective in nitrogen removal. Here, 3 TFCWs with different modifications (baffle, plants, both baffle and plants) were constructed to treat raw domestic sewage and specifically to evaluate the removal efficiencies and mechanism of PPCPs. 24 PPCPs including 7 antibiotics, 8 steroid hormones and 9 biocides were detected in the level of 1.10 ± 0.29 ng/L-799 ± 10.6 ng/L in the influents. Consequently, we found that modification with both baffle and plants significantly influenced the removal of PPCPs. Moreover, the highest removal rates of biocides (97.1 ± 0.29%), steroid hormones (99.8 ± 0.02%), and antibiotics (90.2 ± 1.60%) were achieved via both baffles and plants in TFCWs. Based on the mass balance anal., microbial degradation dominated the removal of PPCPs with a percentage higher than 85.7%, followed by substrate adsorption (5.22 x 10^-2-14.3%) and plant uptake (1.66 x 10^-3-0.44%). Further, 16S rDNA sequencing anal. revealed that the presence of baffle and plants improve the removal efficiency of PPCPs by means of enhancing microbial diversity and changing dominant microorganisms. Moreover, Thaumarchaeota was potentially the key microorganism in the phylum level for PPCPs elimination by TFCWs through LEfSe (linear discriminant anal. (LDA) effect size) anal. These findings provide new insights into the removal of PPCPs in CWs. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide).

4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3) belongs to pyrimidine derivatives. Pyrimidine also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. A Cu-catalyzed and 4-HO-TEMPO-mediated [3 + 3] annulation of commercially available amidines with saturated ketones enables an efficient and facile synthesis of structurally important pyrimidines via a cascade reaction of oxidative dehydrogenation/annulation/oxidative aromatization.Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Three component one-pot synthesis of novel pyrimidino thiazolidin-4-ones catalyzed by activated fly ash was written by Kanagarajan, V.;Thanusu, J.;Gopalakrishnan, M.. And the article was included in Green Chemistry Letters and Reviews in 2009.Safety of 4,6-Diphenylpyrimidin-2-amine This article mentions the following:

The title compounds I (R¹ = H, Cl, MeO; R² = H, Cl, Me, F, MeO; R³ = H, Cl) were synthesized in good yields in a short reaction time by the “one-pot” multicomponent reaction of the corresponding 2-amino-4,6-diarylpyrimidines, benzaldehyde, and thioglycolic acid under microwave irradiation in the presence of activated fly ash catalyst. These compounds characterized by m.p., elemental anal., MS, FT-IR, and one-dimensional NMR (¹H and ¹³C) spectroscopic data. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8Safety of 4,6-Diphenylpyrimidin-2-amine).

4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. Therapy for fungal infections is based mainly on four classes of antifungals: azoles, echinocandins, polyenes, and pyrimidine analogs.Safety of 4,6-Diphenylpyrimidin-2-amine

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Evaluation of growth and biochemical responses of freshwater microalgae Chlorella vulgaris due to exposure and uptake of sulfonamides and copper was written by Li, Shuangxi;Yu, Yunjiang;Gao, Xinxin;Yin, Zhihong;Bao, Jianfeng;Li, Zhuo;Chu, Ruoyu;Hu, Dan;Zhang, Jin;Zhu, Liandong. And the article was included in Bioresource Technology in 2021.COA of Formula: C11H12N4O3S This article mentions the following:

Sulfonamides (SAs) and heavy metals are frequently detected together in livestock wastewater. In this study, evaluations regarding their potentially adverse effects on microalgae and according removals were investigated. Results showed that the growth of C. vulgaris was inhibited by SAs and Cu. There was an obvious recovery period in photosynthetic activity (Fv/Fm), indicating that the damage to the photosystem of microalgae was reversible. The co-existence of SAs and Cu significantly affected the biochem. characteristics, including the activities of antioxidant enzyme and the contents of photosynthetic pigments, proteins and polysaccharides. The addition of Cu obviously promoted the removal efficiencies of SMZ, SMX and SMM, which might be ascribed to the bridging effect of Cu in the bioadsorption of SAs. This study is conducive to understand the changes in the biochem. responses of microalgae under the combined impacts of SAs and Cu, and provides a new insight for the simultaneous removals. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3COA of Formula: C11H12N4O3S).

4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3) belongs to pyrimidine derivatives. Pyrimidine also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. We all know its importance to life – pyrimidine and purine bases are included in the structure of DNA and RNA.COA of Formula: C11H12N4O3S

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Assessment of veterinary antibiotics from animal manure-amended soil to growing alfalfa, alfalfa silage, and milk was written by Huang, Rongcai;Guo, Zitai;Gao, Shengtao;Ma, Lu;Xu, Jianchu;Yu, Zhongtang;Bu, Dengpan. And the article was included in Ecotoxicology and Environmental Safety in 2021.Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide This article mentions the following:

Using animal manure as organic fertilizer to grow fodder crops is causing public health concerns because animal manure is the major reservoir of veterinary antibiotics. In this study, we used a math. model to estimate the risk of human exposure to veterinary antibiotics when using swine manure as organic fertilizer to grow alfalfa (Medicago sativa L.). Alfalfa was planted in a greenhouse and fertilized with swine manure spiked with oxytetracycline (OTC, at 0, 150, and 1500 mg/kg of manure), ofloxacin (OFL, at 0, 15, and 150 mg/kg), or sulfamonomethoxine (SMM, at 0, 5, 15 and 150 mg/kg). Alfalfa was harvested at the budding stage and ensiled for 60 days. Results showed that OTC and OFL could be detected in the alfalfa root, stem, and leaf with a concentration ranging from 8.85 to 59.17 μg OTC /kg and from 1.50 to 4.10 μg OFL/kg dry matter, but SMM could only be detected in the root ranging from 29.10 to 63.75 μg/kg dry matter. The ensiling for 60 days decreased the OFL concentration by 68.7% but only slightly decreased the OTC concentration The maximum daily exposures of humans to OTC and OFL through liquid milk consumption were estimated to be 5.84E-8 and 1.63E-8 μg, resp., both of which are well below the intake levels of OTC (72 μg) and OFL (54 μg) mandated by the European Union. The results of the present study indicate that using swine manure as organic fertilizer to grow alfalfa poses a limited risk for human exposure to veterinary antibiotics through the consumption of liquid milk. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide).

4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3) belongs to pyrimidine derivatives. The pyrimidine ring system has wide occurrence in nature as substituted and ring fused compounds and derivatives. As nucleotides in DNA and RNA, pyrimidine nucleotide derivatives have a wide range of biological applications. For example, pyrimidine derivatives are useful in DNA repair studies involving cancer and epigenetics.Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

In situ application of the diffusive gradients in thin film technique in aquaculture ponds for monitoring antibiotics, hormones, and herbicides was written by Chen, Yiqin;Wen, Ju;Wu, Meng;Li, Juan-Ying;Wang, Qian;Yin, Jie. And the article was included in Environmental Science and Pollution Research in 2022.Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide This article mentions the following:

In recent years, as the abuse of antibiotics, hormones, and herbicides has worsened in aquaculture industry, it is important to monitor the concentrations of those trace contaminants in aquaculture water more effortlessly. The aim of this study was to develop a reliable sampling method for chem. monitoring in aquaculture ponds based on the technique of diffusive gradients in thin films (DGT). A binding material (XDA-1 resin) with high adsorption capacity for antibiotics, hormones, and herbicides was selected. In laboratory, the diffusion coefficients of 11 antibiotics, 3 hormones, and 3 herbicides of the XDA-1-DGT devices were tested and ranged from 1.0×10-6 to 8.7×10-5 cm2/s. During the in situ application of XDA-1-DGT devices in different aquaculture ponds, concentrations of 11 antibiotics, 3 hormones, and 3 herbicides in aquaculture water (CSOLN) via grab sampling were also analyzed and found ranging from 0.03 to 6.3 ng/L, lower than the results based on DGT (CDGT) (1.2-1.3×102 ng/L). The values of CDGT/CSOLN were larger than one unit, suggesting that the rates of resupply of target chems. (antibiotics, hormones, and herbicides) by the desorption and diffusion of pond water were higher than the rates of uptake by XDA-1-DGT, and pond water was proved a sufficient reservoir of antibiotics for DGT application. The value of Log (CDGT/CSOLN) of 1.1 derived from the application in the aquaculture ponds of 14 regions in Eastern China can be a reference value for future chem. monitoring based on DGT technique. And the accuracy of this value was found hardly affected by the phys. and chem. properties of chems. with pKa ranging from -1 to 12, Log Kow ranging from 0 to 4.5, and Log solubility ranging from 0.0 to 4.0. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide).

4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3) belongs to pyrimidine derivatives. The pyrimidine derivatives can easily interact with enzymes, genetic materials, and bio components within the cell. A Cu-catalyzed and 4-HO-TEMPO-mediated [3 + 3] annulation of commercially available amidines with saturated ketones enables an efficient and facile synthesis of structurally important pyrimidines via a cascade reaction of oxidative dehydrogenation/annulation/oxidative aromatization.Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) β Agonist was written by Zheng, Yajun;Zhuang, Linghang;Fan, Kristi Yi;Tice, Colin M.;Zhao, Wei;Dong, Chengguo;Lotesta, Stephen D.;Leftheris, Katerina;Lindblom, Peter R.;Liu, Zhijie;Shimada, Jun;Noto, Paul B.;Meng, Shi;Hardy, Andrew;Howard, Lamont;Krosky, Paula;Guo, Joan;Lipinski, Kerri;Kandpal, Geeta;Bukhtiyarov, Yuri;Zhao, Yi;Lala, Deepak;Van Orden, Rebecca;Zhou, Jing;Chen, Guozhou;Wu, Zhongren;McKeever, Brian M.;McGeehan, Gerard M.;Gregg, Richard E.;Claremon, David A.;Singh, Suresh B.. And the article was included in Journal of Medicinal Chemistry in 2016.Name: Ethyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate This article mentions the following:

This article describes the application of Contour to the design and discovery of a novel, potent, orally efficacious liver X receptor β (LXRβ) agonist ((R)-(2-(4-(4-(hydroxymethyl)-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methanol (17)). Contour technol. is a structure-based drug design platform that generates mols. using a context perceptive growth algorithm guided by a contact sensitive scoring function. The growth engine uses binding site perception and programmable growth capability to create drug-like mols. by assembling fragments that naturally complement hydrophilic and hydrophobic features of the protein binding site. Starting with a crystal structure of LXRβ and a docked 2-(methylsulfonyl)benzyl alc. fragment, Contour was used to design agonists containing a piperazine core. Compound (17) binds to LXRβ with high affinity and to LXRα to a lesser extent, and induces the expression of LXR target genes in vitro and in vivo. This mol. served as a starting point for further optimization and generation of a candidate which is currently in human clin. trials for treating atopic dermatitis. In the experiment, the researchers used many compounds, for example, Ethyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate (cas: 187035-79-6Name: Ethyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate).

Ethyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate (cas: 187035-79-6) belongs to pyrimidine derivatives. Heterocyclic compounds bearing the pyrimidine core are of tremendous interest as they constitute an important class of natural and synthetic compounds exhibiting diverse useful biological activities that hold attractive potential for clinical translation as therapeutic agents in alleviation of a myriad of diseases. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.Name: Ethyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Synthesis of Benzazolyl Pyrimidines Under Ultrasonication and Their Antimicrobial Activity was written by Kayathi, Narendra Babu;Sowmya, Donthamsetty V.;Adivireddy, Padmaja;Venkatapuram, Padmavathi. And the article was included in Journal of Heterocyclic Chemistry in 2018.Related Products of 40230-24-8 This article mentions the following:

The benzoxazolyl/benzothiazolyl/benzimidazolyl pyrimidines were prepared under ultrasonication in the presence of pyridine/dimethylaminopyridine and triethylamine. Better yields were recorded in 4-(N,N-dimethylamino)pyridine and Et₃N. The presence of electron withdrawing chloro, bromo, and nitro substituents enhanced antimicrobial activity (N-(benzo[d]thiazol-2-ylmethyl)-4,6-bis(4-chlorophenyl) pyrimidin-2-amine, N-(benzo[d]thiazol-2-ylmethyl)-4,6-bis(4-nitrophenyl) pyrimidin-2-amine, N-((1H-benzo[d]imidazol-2-yl)methyl)-4,6-bis(4-nitrophenyl)pyrimidin-2-amine: min. inhibitory concentration = 6.25 μg/well against Bacillus subtilis; N-(benzo[d]thiazol-2-ylmethyl)-4,6-bis(4-nitrophenyl) pyrimidin-2-amine, N-((1H-benzo[d]imidazol-2-yl)methyl)-4,6-bis(4-nitrophenyl)pyrimidin-2-amine: min. inhibitory concentration = 6.25 μg/well against Aspergillus niger). In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8Related Products of 40230-24-8).

4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. The pyrimidine derivatives can easily interact with enzymes, genetic materials, and bio components within the cell. As nucleotides in DNA and RNA, pyrimidine nucleotide derivatives have a wide range of biological applications. For example, pyrimidine derivatives are useful in DNA repair studies involving cancer and epigenetics.Related Products of 40230-24-8

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia