In 2015,Sythana, Suresh Kumar; Bhagat, Pundlik R. published 《Metal free C-O bond formation in electron deficient aromatic compounds mediated by tetrabutylammonium hydroxide : application to nimesulide and paracetamol》.Journal of the Indian Chemical Society published the findings.Category: pyrimidines The information in the text is summarized as follows:
A mild and efficient method for carbon-oxygen bond formation for the synthesis of aryl ethers has been demonstrated via reaction of aromatic chloro compounds and alcs. mediated by tetrabutylammonium hydroxide (TBAH). The protocol is free from the metal alkoxides, inorganic bases or metal catalysts. This methodol. has been applied for synthesis of paracetamol and nimesulide intermediates. After reading the article, we found that the author used 2,4,6-Trichloropyrimidine(cas: 3764-01-0Category: pyrimidines)
2,4,6-Trichloropyrimidine(cas: 3764-01-0) is a member of organic chlorides. Organic chloride content in crude oil can be detected through specialized laboratory analysis. Care and attention are essential while sampling and testing.Category: pyrimidines
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia