Sparatore, Anna published the artcilePharmacological profile of a novel H2S-releasing aspirin, Recommanded Product: N,N-Dimethylpyrimidin-4-amine, the publication is Free Radical Biology & Medicine (2009), 46(5), 586-592, database is CAplus and MEDLINE.
The pharmacol. profile of a new, safe, and effective hydrogen sulfide (H2S)-releasing derivative of aspirin (ACS14) is described. We report the synthesis of ACS14, and of its deacetylated metabolite (ACS21), the preliminary pharmacokinetics, and its in vivo metabolism, with the H2S blood plasma levels after i.v. administration in the rat. ACS14 maintains the thromboxane-suppressing activity of the parent compound, but seems to spare the gastric mucosa, by affecting redox imbalance through increased H2S/glutathione formation, heme oxygenase-1 promoter activity, and isoprostane suppression.
Free Radical Biology & Medicine published new progress about 31401-45-3. 31401-45-3 belongs to pyrimidines, auxiliary class Pyrimidine,Amine, name is N,N-Dimethylpyrimidin-4-amine, and the molecular formula is Al2H32O28S3, Recommanded Product: N,N-Dimethylpyrimidin-4-amine.
Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/Pyrimidine,
Pyrimidine – Wikipedia