Some scientific research about 4,6-Dimethyl-N-phenyl-2-pyrimidinamine

At the same time, in my other blogs, there are other synthetic methods of this type of compound,53112-28-0, 4,6-Dimethyl-N-phenyl-2-pyrimidinamine, and friends who are interested can also refer to it.

With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.53112-28-0, name is 4,6-Dimethyl-N-phenyl-2-pyrimidinamine, molecular formula is C12H13N3, molecular weight is 199.2517, as common compound, the synthetic route is as follows.Safety of 4,6-Dimethyl-N-phenyl-2-pyrimidinamine

EXAMPLE 5 Methylsulphonyl isocyanate (3.15 g) was added dropwise to a solution of 2-anilino-4,6-dimethylpyrimidine (3.98 g) in toluene (40 ml). The mixture was then stirred for 2 hours at room temperature. The solid was separated and dried in vacuo, to give 1-(4,6-dimethylpyrimidine-2-yl)-3-methylsulphonyl-1-phenylurea, m.p. 186-192. (Compound 5).

At the same time, in my other blogs, there are other synthetic methods of this type of compound,53112-28-0, 4,6-Dimethyl-N-phenyl-2-pyrimidinamine, and friends who are interested can also refer to it.

Reference:
Patent; Schering Agrochemicals Ltd.; US4783459; (1988); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia