In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 29274-24-6, name is 5-Chloropyrazolo[1,5-a]pyrimidine, the common compound, a new synthetic route is introduced below. SDS of cas: 29274-24-6
To 5-chloropyrazolo[l,5-a]pyrimidine (200 mg, 1.31mmol) in 1.5ml DMF was added POCI3 (358 3.92 mmol). The reaction was stirred at room temperature overnight. The mixture was cooled to 0 C in ice bath and the then neutralized with 6M NaOH. The solid formed was isolated by filtration and air dried to give 165 mg of 5-chloropyrazolo[l,5- a]pyrimidine-3-carbaldehyde as yellow solid (70% yield). LCMS (M+l=182)
The synthetic route of 29274-24-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; CYLENE PHARMACEUTICALS INC.; HADDACH, Mustapha; RYCKMAN, David; RAFFAELE, Nicholas; WO2011/31979; (2011); A1;,
Pyrimidine | C4H4N2 – PubChem,
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