Application of 2908-71-6, Adding some certain compound to certain chemical reactions, such as: 2908-71-6, name is 5-(Bromomethyl)-2-methylpyrimidin-4-amine hydrobromide,molecular formula is C6H9Br2N3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2908-71-6.
On the o ther hand, trisdibenzylieneacetone dipalladium (1.1 mg, 1.2 **mol) and the NMPsolution (200 muL) of triotolyl phosphine (5.8 mg, 19.1 **mol) were prepared for thereaction container of the sign synthesizer unit, and it installed in the room temperature. Thesolution in a reaction container was installed in 10 20 quota which blows a [ C] methyliodide. Then, a [ C] methyl iodide is blown into a reaction container by the gas mass flow of6080 mL/min, The NMP solution (100 muL) of the tin precursor 2 (5.0 mg, 11.9 **mol), CuBr(0.9 mg, 5.9 **mol), and CsF (2.3 mg, 14.9 **mol) was added there, and it heated for 3minutes at 100 degrees C. Then, the DMF solution (100 **L) of 4amino5(bromomethyl)2methylpyrimidine bromate (50 mg, 176.7 **mol) was added, and it heated for 7 minutes at150 degrees C, blowing nitrogen gas by the flow rate of 20 mL/min. After diluting the obtainedreaction solution with the washing liquid (acetonitrile: water =1:1) of 1.2 mL, it filtered usingthe filter. The fraction which presents preparative isolation HPLC with a filtrate (refer to Fig.1),and contains the Csign thiamin 4 isolated preparatively was concentrated in vacuum in theevaporator. Preparative isolation HPLC was again presented with the filtrate obtained bycarrying out filter filtration of the concentrate (refer to Fig.2). The fraction containing the 11C-thiamin 4 isolated preparatively was put into the membrane filter at the sterile vialthrough the concentrate obtained by concentrating in vacuum in an evaporator.
According to the analysis of related databases, 2908-71-6, the application of this compound in the production field has become more and more popular.
Reference:
Patent; RIKEN; Watanabe, Yasuyoshi; Suzuki, Masaaki; Doi, Hisashi; Nozaki, Satoshi; Kanazawa, Shomasaru; Mawatari, Aya; (25 pag.)JP6037330; (2016); B2;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia