Seela, Frank; Winkeler, Heinz Dieter published the artcile< 2-Amino-7-β-D-arabinofuranosyl-4-methoxy-7H-pyrrolo[2,3-d]pyrimidine: a facile preparation and anomerization of a 7-deazapurine nucleoside>, Reference of 84955-32-8, the main research area is arabinofuranosylpyrrolopyrimidine amino; pyrrolopyrimidine arabinofuranosyl amino; deazapurine nucleoside preparation anomerization; glycosylation aminopyrrolopyrimidine arabinofuranosyl bromide.
Phase-transfer glycosylation of 2-amino-4-methoxy-7H-pyrrolo[2,3-d]pyrimidine with 2,3,5-tri-O-benzyl-D-arabinofuranosyl bromide in C6H6-50% aqueous NaOH-tetrabutylammonium hydrogen sulfate gave two anomeric glycosylation products I and II (R = PhCH2). Removal of the benzyl groups with BCl3 yielded I and II (R = H). Treatment of I and II (R = H) with 2M HCl under N caused anomerization and demethylation without glycosylic cleavage, and reflected the extraordinary stability of pyrrolo[2,3-d]pyrimidine nucleosides towards hydrolysis. The conversion of I and II (R = H) into ara-7-deazaguanosine or its a anomer was accomplished with anhydrous acid.
Carbohydrate Research published new progress about Glycosylation. 84955-32-8 belongs to class pyrimidines, and the molecular formula is C7H8N4O, Reference of 84955-32-8.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia