Riand, Jacques published the artcileProton and carbon-13 nuclear magnetic resonance studies of substituted pyrimidines. Part 3. Hindered internal rotation in some 4-(NN-dimethylamino)pyrimidines, Application In Synthesis of 31401-45-3, the publication is Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) (1979), 1248-52, database is CAplus.
The free energy of activation for internal rotation about the C-N exocyclic bond of substituted 4-(N,N-dimethylamino)pyrimidines was determined using 1H and 13C NMR line-shape anal. Substituent effects on the rotational barrier of the NMe2 group were evaluated. The rotational barrier is higher for a NMe2 group in the 4-position than for one in the 2 position. There is a linear correlation between the free energies of activation and 1J(C,H) coupling constants for the 4-NMe2 group.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) published new progress about 31401-45-3. 31401-45-3 belongs to pyrimidines, auxiliary class Pyrimidine,Amine, name is N,N-Dimethylpyrimidin-4-amine, and the molecular formula is C6H9N3, Application In Synthesis of 31401-45-3.
Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/Pyrimidine,
Pyrimidine – Wikipedia