Pyrimidines

On December 24, 2014, Wang, Heshan published a patent.Application of 23256-42-0 The title of the patent was Coating material containing white ointment and manufacture method. And the patent contained the following:

Title coating material is manufactured from white ointment 1-2, trimethoprim lactate 0.5-1, tetrabutylammonium bromide 1-2, sodium carbonate 2-3, allyl poly(ethylene glycol) 1-2, celestite powder 6-10, precipitated silica 5-8, dibutyltin dilaurate 0.8-1, polyacrylamide 0.8-1, styrene 120-160, Me acrylate 80-100, Bu methacrylate 40-60, ammonium peroxydisulfate 3-4, OP-10 6-8, bonding additive 5-7, and deionized water 500-600 weight parts. The bonding additive is manufactured from isobornyl acrylate 6-8, acrylic-silicone emulsion 25-30, microcapsule rose essential oil 2-3, dimethylaminoethyl methacrylate 4-6, potassium persulfate 1-2, redwood powder 2-3, poly(N-vinylpyrrolidone) 0.6-1, and deionized water 10-16 weight parts. The invention also provides methods for manufacturing the title coating material and the bonding additive. The white ointment in the title coating material effectively improves compatibility among the materials, promotes uniform and leveling of coating film, and improves film-forming effect and adhesion. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Application of 23256-42-0

The Article related to coating white ointment manufacture, Coatings, Inks, and Related Products: Acrylic and Water-Sol (Electrophoretic) Resin Coatings and other aspects.Application of 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On September 30, 2013, Bakavoli, Mehdi; Eshghi, Hossein; Shiri, Ali; Afrough, Toktam; Tajabadi, Javad published an article.Product Details of 626-48-2 The title of the article was Synthesis, characterization and theoretical evaluations of HMDS promoted chemoselective O-alkylation of uracils. And the article contained the following:

The sodium salts of the conjugated bases of uracils undergo highly chemoselective O4-monoalkylation when treated with various alkyl halides in dry DMF, while the use of Me iodide results in N1+N3-dimethylation. Theor. evaluations of the chemo- and regioselectivity along with x-ray crystallog. data are presented. The experimental process involved the reaction of 6-Methylpyrimidine-2,4(1H,3H)-dione(cas: 626-48-2).Product Details of 626-48-2

The Article related to hmds chemoselective o alkylation uracil, Heterocyclic Compounds (More Than One Hetero Atom): Other 6-Membered Rings, Two Hetero Atoms and other aspects.Product Details of 626-48-2

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On October 28, 2013, Bakavoli, Mehdi; Eshghi, Hossein; Shiri, Ali; Afrough, Toktam; Tajabadi, Javad published an article.Synthetic Route of 626-48-2 The title of the article was Synthesis, characterization and theoretical evaluations of HMDS promoted chemoselective O-alkylation of uracils [Erratum to document cited in CA159:399291]. And the article contained the following:

On page 8470, the third paragraph in the first column contained incorrect text; the corrected text is given. On page 8474, an important citation was omitted from the Exptl. section; the omitted citation is given. The experimental process involved the reaction of 6-Methylpyrimidine-2,4(1H,3H)-dione(cas: 626-48-2).Synthetic Route of 626-48-2

The Article related to erratum hmds chemoselective o alkylation uracil, Heterocyclic Compounds (More Than One Hetero Atom): Other 6-Membered Rings, Two Hetero Atoms and other aspects.Synthetic Route of 626-48-2

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On December 16, 2015, Liang, Ruiyong; Gao, Hai published a patent.SDS of cas: 23256-42-0 The title of the patent was Environmentally friendly waterborne coating compositions. And the patent contained the following:

The compositions, having low VOC content, contain waterborne acrylic emulsions 91-100, polydicyclopentadiene 1-2, ammonium molybdate 0.5-1, iron trifluoroacetylacetonate 0.1-0.2, polypropylene glycol 1-2, potassium silicate 1-2, octyl epoxystearate 2-4, 2-mercaptobenzimidazole 0.5-1, ultrafine barium sulfate 10-12, polymethyl acrylate 2-3, dodecyl di-Me amine oxide 0.3-1, flame retardant aids 2-4, ethylene glycol Bu ether 2-3, and deionized water 20-30 parts. The flame retardant aids contain microcapsulated red phosphorus, polycarbonates, aluminum magnesium silicate, lithium-based bentonite, trimethoprim lactate, trimethylolpropane, and isooctyl acrylate. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).SDS of cas: 23256-42-0

The Article related to flame retardant acrylic emulsion waterborne coating composition, Coatings, Inks, and Related Products: Acrylic and Water-Sol (Electrophoretic) Resin Coatings and other aspects.SDS of cas: 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On January 7, 2015, Sun, Jufu; Dai, Yujun; Zhu, Penxin published a patent.Computed Properties of 23256-42-0 The title of the patent was Antibacterial anticorrosive coatings. And the patent contained the following:

The coatings contain trimethoprim lactate 0.7-1, polyoxymethylene 2-3, ammonium polyphosphate 2-3, turpentine 0.6-1, illite powders 6-8, β-hydroxyalkyl amides 1-2, 2-bromo-4-methylphenol 1-2, precipitated silica 6-10, crosslinking agent TAC 0.5-1, diisocyanates 0.4-1, styrene 140-200, epoxidized soybean oil 2-3, deionized water 500-600, isooctyl acrylate 140-200, sodium persulfate 3-6, OP-10 5-7, and bonding aids 4-5 parts. The bonding aids are prepared from alumina sol, ammonium aluminum sulfate, lanolin, polyethylene glycol dimethacrylate, anhydrous ethanol, isooctyl acrylate, potassium sulfate, OP-10, rosewood micropowders, and deionized water. The coatings have good adhesion and weather resistance. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Computed Properties of 23256-42-0

The Article related to antibacterial anticorrosive acrylate coating weather resistance, Coatings, Inks, and Related Products: Acrylic and Water-Sol (Electrophoretic) Resin Coatings and other aspects.Computed Properties of 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Firoozi, Neda; Bakavoli, Mehdi; Eshghi, Hossein; Ramezanian, Navid published an article in 2017, the title of the article was Regioselective synthesis of new 5-methyl-5H-pyrimido[4′,5′:4,5][1,3]thiazino [3,2-a]perimidines.HPLC of Formula: 626-48-2 And the article contains the following content:

A convenient and efficient regioselective synthesis of new pyrimido[4′,5′:4,5] [1,3]thiazino[3,2-a]perimidines I (R = pyrrolidin-1-yl, 4-methylpiperidin-1-yl, cyclohexylamino, methylamino, etc.) was described through intermol. heterocyclization of 2,4-dichloro-5-(chloromethyl)-6-methylpyrimidine and 1H-perimidine-2(3H)-thione in short reaction times under mild conditions. The experimental process involved the reaction of 6-Methylpyrimidine-2,4(1H,3H)-dione(cas: 626-48-2).HPLC of Formula: 626-48-2

The Article related to pyrimido thiazino perimidine preparation regioselective, chloromethyl dichloro methylpyrimidine perimidinyl thione preparation heterocyclization, Heterocyclic Compounds (More Than One Hetero Atom): Other 6-Membered Rings, Two Hetero Atoms and other aspects.HPLC of Formula: 626-48-2

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Kasradze, V. G.; Ignatyeva, I. B.; Khusnutdinov, R. A.; Suponitskii, K. Yu.; Antipin, M. Yu.; Yunusov, M. S. published an article in 2012, the title of the article was Oxidative halogenation of 6-methyluracil.Formula: C5H6N2O2 And the article contains the following content:

An efficient method has been developed for the preparation of halo derivatives of 6-methyluracil by employing oxidative halogenation. Elemental halogens and potassium halides were used as the halogenating agents, while NaNO3 and H2O2 were used as the oxidizing agents. Iodination of 6-methyluracil leads to 5-iodo-6-methyluracil as the single reaction product, while bromination or chlorination lead to 5-halo-6-methyluracil, 5,5-dihalo-6-hydroxy-6-methyl-5,6-dihydrouracil, or their mixture depending on the acidity of the medium and the ratio of the substrate and reagents. Bromination of 5-chloro-6-methyluracil leads to 5-bromo-5-chloro-6-hydroxy-6-methyl-5,6-dihydrouracil, while chlorination of 6-methyl-, 5-bromo-6-methyl-, and 5-chloro-6-methyluracils using gaseous chlorine yields 5,5-dichloro-6-hydroxy-6-methyl-5,6-dihydrouracil. The experimental process involved the reaction of 6-Methylpyrimidine-2,4(1H,3H)-dione(cas: 626-48-2).Formula: C5H6N2O2

The Article related to oxidative halogenation methyluracil crystallog, Physical Organic Chemistry: Oxidation-Reduction, Including Dehydrogenation and Hydrogenolysis and other aspects.Formula: C5H6N2O2

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On December 31, 2015, Zimin, Yu. S.; Khairullina, L. R.; Kutlugil’dina, G. G.; Mustafin, A. G. published an article.COA of Formula: C5H6N2O2 The title of the article was Chemiluminescence in the reaction of ozone with 6-methyluracil in aqueous solutions. And the article contained the following:

Chemiluminescence in the visible part of the spectrum during the oxidation of 6-methyluracil with ozone in aqueous solutions was found. The kinetics of variation of the luminescence intensity was studied in the temperature range 287-333 K, and the activation parameters of the process were determined The experimental process involved the reaction of 6-Methylpyrimidine-2,4(1H,3H)-dione(cas: 626-48-2).COA of Formula: C5H6N2O2

The Article related to methyluracil ozone chemiluminescence oxidation kinetics, Physical Organic Chemistry: Oxidation-Reduction, Including Dehydrogenation and Hydrogenolysis and other aspects.COA of Formula: C5H6N2O2

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On May 31, 2012, Akhatova, G. R.; Safarova, I. V.; Gerchikov, A. Ya.; Enikeev, A. A. published an article.Name: 6-Methylpyrimidine-2,4(1H,3H)-dione The title of the article was Kinetics and mechanism of the reactions of uracil with hydrogen peroxide in aqueous solutions. And the article contained the following:

The kinetics of the reactions of 5-hydroxy-6-methyluracil and 6-methyluracil with hydrogen peroxide in aqueous solutions has been investigated. The reactions proceed via two competitive mechanisms, namely, free-radical and nonradical ones. The iron ions present in water as impurities make possible the free-radical mechanism. The experimental process involved the reaction of 6-Methylpyrimidine-2,4(1H,3H)-dione(cas: 626-48-2).Name: 6-Methylpyrimidine-2,4(1H,3H)-dione

The Article related to uracil hydrogen peroxide reaction kinetics mechanism iron, Physical Organic Chemistry: Oxidation-Reduction, Including Dehydrogenation and Hydrogenolysis and other aspects.Name: 6-Methylpyrimidine-2,4(1H,3H)-dione

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On February 16, 2012, Tang, Pengcho; Li, Xin; Wang, Bin; Li, Xiangqin; Chen, Yang; Chen, Xuejiang; Zhang, Lei; Song, Min published a patent.Reference of 6,7-Dihydro-5H-pyrrolo[3,4-d]pyrimidine hydrochloride The title of the patent was Preparation of phthalazinone derivatives useful as antitumor agents. And the patent contained the following:

The invention relates to phthalazinone derivatives (e.g., I), processes for preparing them, pharmaceutically preparations comprising them, and their use as poly (ADP-ribose) polymerase (PARP) inhibitors for treating cancer. For instance, the invention compound I was prepared and gave a PARP-1 inhibition IC50 value of 0.5 nM. The experimental process involved the reaction of 6,7-Dihydro-5H-pyrrolo[3,4-d]pyrimidine hydrochloride(cas: 1187830-46-1).Reference of 6,7-Dihydro-5H-pyrrolo[3,4-d]pyrimidine hydrochloride

The Article related to phthalazinone derivative preparation antitumor parp inhibitor, Heterocyclic Compounds (More Than One Hetero Atom): Pyridazines, Cinnolines, and Phthalazines and other aspects.Reference of 6,7-Dihydro-5H-pyrrolo[3,4-d]pyrimidine hydrochloride

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia