The pyrimidine ring system has wide occurrence in nature as substituted and ring fused compounds and derivatives, including the nucleotides cytosine, thymine and uracil, thiamine (vitamin B1) and alloxan. 109-12-6, formula is C4H5N3, Name is Pyrimidin-2-amine. It is also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. Safety of Pyrimidin-2-amine.
Olyaei, Abolfazl;Mohamadi, Amir;Rahmani, Nilufar research published 《 Green synthesis of new lawsone enaminones and their Z/E(C=C)-isomerization induced by organic solvent》, the research content is summarized as follows. The synthesis of a new class of lawsone enaminone derivatives by using lawsone, tri-Et orthoformate and aromatic amines in the presence of guanidinium chloride under solvent-free conditions was developed. Investigation of 1H-NMR spectra indicated that lawsone enaminones exist in the ketoenamine tautomeric form and underwent Z/E-isomerization with respect to the C=C bond in DMSO-d6 at room temperature Furthermore, intramol. hydrogen bonds were observed in the synthesized compounds This method has some advantages including short reaction times, high to excellent yields, simple work-up procedure and very easy purification of products by non-chromatog. methods.
109-12-6, 2-Aminopyrimidine is a useful research compound. Its molecular formula is C4H5N3 and its molecular weight is 95.1 g/mol. The purity is usually 95%.
2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically., Safety of Pyrimidin-2-amine
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia