Category: pyrimidines. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 5-Methylfuran-2(3H)-one, is researched, Molecular C5H6O2, CAS is 591-12-8, about Remote Functionalization of 4-(Alk-1-en-1-yl)-3-Cyanocoumarins via the Asymmetric Organocatalytic 1,6-Addition. Author is Romaniszyn, Marta; Gronowska, Katarzyna; Albrecht, Lukasz.
An organocatalytic 1,6-addition using 4-(alk-1-en-1-yl)-3-cyanocoumarins as acceptors was developed. Dienolates derived from 5-substituted-furan-2(3H)-ones have been employed as pronucleophiles, therefore, enabling the synthesis of hybrid mols. bearing two biol. relevant units I [R = H, 7-MeO, 6-Br, etc.; R1 = Me, allyl, Ph, etc.; R2 = H, Me; R3 = H, Me]. Appropriate design of substrates and the application of quinine-derived catalyst resulted in very good site-selectivity as well as chem. and stereochem. efficiency of the process.
There is still a lot of research devoted to this compound(SMILES：O=C1OC(C)=CC1)Category: pyrimidines, and with the development of science, more effects of this compound(591-12-8) can be discovered.
Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia