On December 18, 2020, Nguyen, Kim; Kubota, Miles; Arco, Jon del; Feng, Chao; Singha, Monika; Beasley, Samantha; Sakr, Jasmine; Gandhi, Sunil P.; Blurton-Jones, Matthew; Fernandez Lucas, Jesus; Spitale, Robert C. published an article.COA of Formula: C5H6N2O3 The title of the article was A Bump-Hole Strategy for Increased Stringency of Cell-Specific Metabolic Labeling of RNA. And the article contained the following:
Profiling RNA expression in a cell-specific manner continues to be a grand challenge in biochem. research. Bioorthogonal nucleosides can be used to track RNA expression; however, these methods currently have limitations due to background and incorporation of analogs into undesired cells. Herein, the authors design and demonstrate that uracil phosphoribosyltransferase can be engineered to match 5-vinyluracil for cell-specific metabolic labeling of RNA with exceptional specificity and stringency. The experimental process involved the reaction of 5-(Hydroxymethyl)pyrimidine-2,4(1H,3H)-dione(cas: 4433-40-3).COA of Formula: C5H6N2O3
The Article related to rna expression vinyl uracil metabolic labeling, Biochemical Methods: Other (Not Covered At Other Subsections) and other aspects.COA of Formula: C5H6N2O3
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia