Adding a certain compound to certain chemical reactions, such as: 3438-61-7, 5-Amino-4-methylpyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, SDS of cas: 3438-61-7, blongs to pyrimidines compound. SDS of cas: 3438-61-7
In an oven-dried 500 mL two-necked round-bottomed flask 1-bromo-2-nitrobenzene (18.33 g, 91 mmol), 4-methylpyrimidin-5-amine (9 g, 82 mmol), cesium carbonate (53.7 g, 165 mmol), Pd2(dba)3 (1.510 g, 1.649 mmol) and 2,2?-bis(diphenylphosphanyl)-1,1?-binaphthalene (BINAP) (5.14 g, 8.25 mmol) were dissolved in toluene (180 ml) under nitrogen to give a red suspension. The reaction mixture was degassed and heated to 120 C. for 16 h. The mixture was cooled down, diluted with ethyl acetate, washed with brine, filtered through celite and evaporated, providing 4-methyl-N-(2-nitrophenyl)pyrimidin-5-amine as a red solid (10.1 g, 53% yield).
At the same time, in my other blogs, there are other synthetic methods of this type of compound,3438-61-7, 5-Amino-4-methylpyrimidine, and friends who are interested can also refer to it.
Reference:
Patent; Universal Display Corporation; Tsai, Jui-Yi; Xia, Chuanjun; Yeager, Walter; Dyatkin, Alexey Borisovich; (207 pag.)US2017/324049; (2017); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia