Application of 60025-06-1, Adding some certain compound to certain chemical reactions, such as: 60025-06-1, name is 1-(4,6-Dichloropyrimidin-5-yl)ethanone,molecular formula is C6H4Cl2N2O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 60025-06-1.
Step 2 – Synthesis of Compound 13B; Compound 13A (860 mg) was dissolved in DMF (5 mL) and to the resulting solution was added DIPEA (1.1 mL, 1.4 eq), followed by compound 12B (1.36 g, 1.4 eq). The resulting reaction was allowed to stir at room temperature under nitrogen atmosphere for 2.5 hours, then the reaction mixture was heated at 60 0C and allowed to stir at this temperature for an additional 19 hours. The reaction mixture was cooled to room temperature and concentrated in vacuo to provide a brown oily residue which was purified using flash column chromatography on silica gel to provide compound 13B (192 mg, 12%).
According to the analysis of related databases, 60025-06-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; SCHERING CORPORATION; NEELAMKAVIL, Santhosh, Francis; BOYLE, Craig, D.; HARRIS, Joel, M.; STAMFORD, Andrew, W.; HAO, Jinsong; NEUSTADT, Bernardt, R.; CHACKALAMANNIL, Samuel; XIA, Yan; GREENLEE, William, J.; WO2010/9207; (2010); A1;,
Pyrimidine | C4H4N2 – PubChem,
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