On April 30, 1980, Melby, Kjetil; Midtvedt, Tore published an article.Formula: C17H24N4O6 The title of the article was Effects of some antibacterial agents on the phagocytosis of phosphorus-32-labeled Escherichia coli by human polymorphonuclear cells. And the article contained the following:
Gentamicin [1403-66-3], trimethoprim lactate [23256-42-0] cephalothin [153-61-7], colistin [1066-17-7], erythromycin [114-07-8], oxytetracycline [79-57-2], and chloramphenicol [56-75-7] were studied in a phagocytic system. A radiolabeled strain of E. coli was used as test bacterium and human polymorphonuclear cells were used as phagocytes. Except for trimethoprim and cephalothin, there was a tendency towards depression of the process of phagocytosis in the presence of high concentrations of the various antibiotics. Colistin in a high concentration (83 μg/mL) exerted the most significant effect. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Formula: C17H24N4O6
The Article related to phagocytosis antibiotic, Pharmacodynamics: Effects On Test Systems and Nonmammals and other aspects.Formula: C17H24N4O6
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia