On July 10, 1975, Holstius, Elvin A.; Alvan, George E. published a patent.Application of 23256-42-0 The title of the patent was Antibacterial, pharmaceutical ear and eye formulations. And the patent contained the following:
An aqueous solution or an ointment, containing sulfacetamide (I) [144-80-9] 0.1-0.5 trimethoprim hemisulfate (II) [56585-33-2] 0.1-0.5, and polymyxin 0.05-0.15 weight/volume %, was stable and possessed a wide spectrum of antibacterial activity. In an example, 100 ml aqueous solution contained 0.50 I, II corresponding to 0.10 g trimethoprim free base, 0.15 polymyxin B sulfate [1405-20-5] 0.001 thiomersal, and 0.83 g NaCl. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Application of 23256-42-0
The Article related to bactericide ear eye, sulfacetamide bactericide ear eye, trimethoprim bactericide ear eye, polymixin bactericide ear eye, Pharmaceuticals: Formulation and Compounding and other aspects.Application of 23256-42-0
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia