Extended knowledge of 4595-59-9

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 4595-59-9, 5-Bromopyrimidine.

Related Products of 4595-59-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 4595-59-9, name is 5-Bromopyrimidine. This compound has unique chemical properties. The synthetic route is as follows.

General procedure: Forthe Suzuki-Miyaura reaction, a 50 mL round-bottomed flask was charged with aryl halide(0.5 mmol), arylboronic acid (0.65 mmol), K2CO3 (1 mmol), catalyst (0.002 g; 0.0005 mmol ofPd) and water (4 mL) and stirred at appropriate temperature. The progress of the reaction wasmonitored by thin layer chromatography using aluminum coated TLC plates (Merck) underUV light. At the end of reaction, the mixture was cooled down to room temperature and theproduct diluted with water (10 mL) and extracted with ether (3 x 15 mL). The combinedextract was washed with brine (3 x 15 mL) and dried over Na2SO4. After evaporation of the solventunder reduced pressure, the residue was subjected to column chromatography with ethylacetate/hexane (1:9) as eluent to get the desired product.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 4595-59-9, 5-Bromopyrimidine.

Reference:
Article; Hazarika, Munmi; Borah, Debajit; Bora, Popymita; Silva, Ana R.; Das, Pankaj; PLoS ONE; vol. 12; 9; (2017);,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia