On July 19, 2007, Epp, Jeffrey Brian; Schmitzer, Paul Richard; Ruiz, James Melvin; Balko, Terry William; Siddall, Thomas Lyman; Yerkes, Carla Nanette published a patent.Synthetic Route of 944129-00-4 The title of the patent was Preparation of 2-(polysubstituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids as herbicides.. And the patent contained the following:
Title compounds [I; Q = halo; R1, R2 = H, alkyl, alkenyl, alkynyl, OH, alkoxy, amino, acyl, carboalkoxy, alkylcarbamyl, alkylsulfonyl, trialkylsilyl, dialkylphosphonyl; NR1R2 = 5- or 6-membered saturated ring; Ar = polysubstituted aryl; and agrochem. acceptable derivatives thereof], were prepared Thus, Me 5-chloro-2-(4-chloro-3-ethoxy-2-fluorophenyl)-6-methanesulfonylpyrimidine-4-carboxylate (preparation given) was stirred 3 h with NH3 in dioxane/MeOH to give 54% Me 6-amino-5-chloro-2-(4-chloro-3-ethoxy-2-fluorophenyl)pyrimidine-4-carboxylate. The latter at 140 g/ha post-emergent gave 100% control of Chenopodium album, Abutilon theophrasti, and Helianthus annus. The experimental process involved the reaction of Methyl 6-amino-2-chloropyrimidine-4-carboxylate(cas: 944129-00-4).Synthetic Route of 944129-00-4
The Article related to arylaminohalopyrimidinecarboxylate preparation herbicide, pyrimidinecarboxylate aryl amino halo preparation weed killer, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Synthetic Route of 944129-00-4
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia