Dong, Lefeng team published research on Organic Letters in 2022 | 1722-12-9

1722-12-9, 2-Chloropyrimidine is a monochlorinated pyrimidine with plant growth regulating activity. Chloropyrimidine is a useful reagent in the preparation of antivirals and other biologically active compounds.
2-Chloropyrimidine undergoes cobalt-catalyzed cross-coupling reaction with aryl halides.
2-Chloropyrimidine is a molecule that can be synthesized by the oxidation of pyrimidine with hydrogen peroxide and hydrochloric acid. The reaction proceeds through an electrochemical process in which the oxidation catalyst is a platinum electrode. This reaction is catalyzed by the nucleophilic attack of malonic acid on the chloropyrimidine at the methylene group. This efficient method for making 2-chloropyrimidine has been applied to synthesize aryl halides, including phenyl chloropyrimidine and pyridyl chloropyrimidine, from their corresponding chloride and bromide precursors. The fluorescence properties of 2-chloropyrimidine have been studied in coordination chemistry, where it forms complexes with metal ions such as Mn2+. In this study, it was found that adsorption mechanisms are dependent on molecular size, charge density, kinetic energy, and adsorbent surface area., Product Details of C4H3ClN2

The pyrimidine ring system has wide occurrence in nature as substituted and ring fused compounds and derivatives, 1722-12-9, formula is C4H3ClN2, Name is 2-Chloropyrimidine. including the nucleotides cytosine, thymine and uracil, thiamine (vitamin B1) and alloxan. Product Details of C4H3ClN2.

Dong, Lefeng;Feng, Tingting;Xiong, Dongdong;Xu, Zhiping;Cheng, Jiagao;Xu, Xiaoyong;Shao, Xusheng;Li, Zhong research published 《 Copper(II)-Catalyzed Direct C-H Trifluoroethylation of Heteroarenes》, the research content is summarized as follows. Herein, an efficient method for the copper-catalyzed direct trifluoroethylation of heteroarenes such as 5-(pyrimidin-2-yl)-5H-[1,3]dioxolo[4,5-f]indole, 2-(5-methylfuran-2-yl)pyrimidine, 2-(5-methylthiophen-2-yl)pyrimidine, etc. was reported. The reaction exhibited good compatibility to various substrates, and the desired products such as 5-(pyrimidin-2-yl)-6-(2,2,2-trifluoroethyl)-5H-[1,3]dioxolo[4,5-f]indole, 2-(5-methyl-3-(2,2,2-trifluoroethyl)furan-2-yl/thiophen-2-yl)pyrimidine, etc. were obtained in good yields. Preliminary mechanistic investigations indicates that the trifluoroethyl radical is involved in the catalytic circle.

1722-12-9, 2-Chloropyrimidine is a monochlorinated pyrimidine with plant growth regulating activity. Chloropyrimidine is a useful reagent in the preparation of antivirals and other biologically active compounds.
2-Chloropyrimidine undergoes cobalt-catalyzed cross-coupling reaction with aryl halides.
2-Chloropyrimidine is a molecule that can be synthesized by the oxidation of pyrimidine with hydrogen peroxide and hydrochloric acid. The reaction proceeds through an electrochemical process in which the oxidation catalyst is a platinum electrode. This reaction is catalyzed by the nucleophilic attack of malonic acid on the chloropyrimidine at the methylene group. This efficient method for making 2-chloropyrimidine has been applied to synthesize aryl halides, including phenyl chloropyrimidine and pyridyl chloropyrimidine, from their corresponding chloride and bromide precursors. The fluorescence properties of 2-chloropyrimidine have been studied in coordination chemistry, where it forms complexes with metal ions such as Mn2+. In this study, it was found that adsorption mechanisms are dependent on molecular size, charge density, kinetic energy, and adsorbent surface area., Product Details of C4H3ClN2

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia