Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. 2927-71-1, formula is C4HCl2FN2, Name is 2,4-Dichloro-5-fluoropyrimidine. In nucleic acids, three types of nucleobases are pyrimidine derivatives: cytosine (C), thymine (T), and uracil (U). Formula: C4HCl2FN2.
Choi, Jang-Sik;Hwang, Hae-jun;Kim, Se-Won;Lee, Byung Il;Lee, Jaekyoo;Song, Ho-Juhn;Koh, Jong Sung;Kim, Jung-Ho;Lee, Phil Ho research published 《 Highly potent and selective pyrazolylpyrimidines as Syk kinase inhibitors》, the research content is summarized as follows. A series of pyrazolylpyrimidine scaffold based Syk inhibitors, e.g. I, were synthesized and evaluated for their biol. activities and selectivity. Lead optimization efforts provided compounds with potent Syk inhibition in both enzymic and TNF-α release assay.
Formula: C4HCl2FN2, 2,4-Dichloro-5-fluoropyrimidine is a useful research compound. Its molecular formula is C4HCl2FN2 and its molecular weight is 166.97 g/mol. The purity is usually 95%.
2,4-Dichloro-5-fluoropyrimidine is an aromatic hydrocarbon that has been shown to inhibit the growth of mouse tumor cells in vitro. It also inhibits the production of amines by reacting with industrial chemicals and sodium carbonate. This compound has potent inhibitory activity against autoimmune diseases and cytotoxic potency on mcf-7 cells. Furthermore, 2,4-Dichloro-5-fluoropyrimidine has been shown to have a chlorinating effect on cancer cells., 2927-71-1.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia