On March 31, 2022, Chernikova, I. B.; Yunusov, M. S. published an article.Application In Synthesis of 6-Methylpyrimidine-2,4(1H,3H)-dione The title of the article was On the mechanism of deiodination of 5-iodo-1,3,6-trimethyluracil. And the article contained the following:
Dehalogenation of 5-iodo-1,3,6-trimethyluracil in acidic medium in the presence of either KCl or KBr as the nucleophile sources proceeded as the halophilic reaction to give 1,3,6-trimethyluracil. This compound can be iodinated with ICl or IBr generated in the course of the reaction to recover the starting 5-iodo-1,3,6-trimethyluracil. This reverse process can be suppressed by addition of 6-methyluracil. The plausible reaction mechanism is discussed. The experimental process involved the reaction of 6-Methylpyrimidine-2,4(1H,3H)-dione(cas: 626-48-2).Application In Synthesis of 6-Methylpyrimidine-2,4(1H,3H)-dione
The Article related to iodo trimethyluracil dehalogenation mechanism, Physical Organic Chemistry: Addition, Elimination, and Substitution Reactions and other aspects.Application In Synthesis of 6-Methylpyrimidine-2,4(1H,3H)-dione
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia