Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. One of the three diazines (six-membered heterocyclics with two nitrogen atoms in the ring), it has the nitrogen atoms at positions 1 and 3 in the ring. 109-12-6, formula is C4H5N3, Name is Pyrimidin-2-amine. The pyrimidine ring system has wide occurrence in nature as substituted and ring fused compounds and derivatives, including the nucleotides cytosine, thymine and uracil, thiamine (vitamin B1) and alloxan. Name: Pyrimidin-2-amine.
Chandraprakash, B.;Sarangapani, M. research published 《 Synthesis, characterization, anticancer and antibacterial activity of 4-(benzylidene)-1-(pyrimidin-2-amino)-2-(p-tolyl)-1, 4-dihydro-4H-imidazol-5-one》, the research content is summarized as follows. In present study, conventional synthesis of 4-(benzylidene)-1-(pyrimidin-2-amino)-2-(p-tolyl)-1, 4-dihydro-4H-imidazol-5-ones I [R = H, Me, Cl, etc.; R1 = H, MeO, NO2] was performed. All the synthesized products I were purified through column chromatog. and structures of these compounds were characterized by IR, 1H NMR and mass spectral data. All the final compounds I were screened for their anticancer and antibacterial activity and their efficacy were matched with standard drugs. The synthesized compounds I [R = Me, NO2, MeO, Br; R1 = H, MeO] showed good anticancer activities whereas others exhibited significant activities. The compounds I [R = Cl, MeO, NO2; R1 = H, MeO] has showed maximum antibacterial activity compare with streptomycin as a standard drug.
109-12-6, 2-Aminopyrimidine is a useful research compound. Its molecular formula is C4H5N3 and its molecular weight is 95.1 g/mol. The purity is usually 95%.
2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically., Name: Pyrimidin-2-amine
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia