Category: 65364-63-8

Lapachev, V. V.’s team published research in Tetrahedron Letters in 1978 | CAS: 65364-63-8

Ethyl 2-cyano-2-(pyrimidin-2-yl)acetate(cas: 65364-63-8) is a member of pyrimidine. Pyrimidine derivatives are an important class of N-heterocycles. They are well-known for their wide spectrum of promising biological activities such as antitumors, bactericidals, and fungicidal.Formula: C9H9N3O2

In 1978,Tetrahedron Letters included an article by Lapachev, V. V.; Zagulyaeva, O. A.; Bichkov, S. F.; Mamaev, V. P.. Formula: C9H9N3O2. The article was titled 《Tautomerism in the pyrimidylmethane systems》. The information in the text is summarized as follows:

The tautomerism of pyrimidyl-4-methanes I [R = CH(CN)CO2Et, R1 = Me, CF3; R = CH2NO2, R1 = Me, H] was studied by 13C and 1H NMR methods. In the presence of DMSO pyrimidine, ortho quinoid and para quinoid forms were observed; the tautomeric equilibrium between these forms, especially between pyrimidylidene tautomers, depends strongly on solvent and is more complicated than suggested by H. Feuer and J. P. Lawrence (1972). Pyrimidine-pyrimidylidene equilibrium were also observed in the pyrimidyl-2-methanes II (R = H, R1 = H, Me, Br, Cl, OMe, NMe2; R = Me, Ph, OMe, R1 = H).Ethyl 2-cyano-2-(pyrimidin-2-yl)acetate(cas: 65364-63-8Formula: C9H9N3O2) was used in this study.

Ethyl 2-cyano-2-(pyrimidin-2-yl)acetate(cas: 65364-63-8) is a member of pyrimidine. Pyrimidine derivatives are an important class of N-heterocycles. They are well-known for their wide spectrum of promising biological activities such as antitumors, bactericidals, and fungicidal.Formula: C9H9N3O2

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Oleinik, Irina V.’s team published research in Mendeleev Communications in 1994 | CAS: 65364-63-8

Ethyl 2-cyano-2-(pyrimidin-2-yl)acetate(cas: 65364-63-8) is a member of pyrimidine. Pyrimidine derivatives are an important class of N-heterocycles. They are well-known for their wide spectrum of promising biological activities such as antitumors, bactericidals, and fungicidal.Quality Control of Ethyl 2-cyano-2-(pyrimidin-2-yl)acetate

Quality Control of Ethyl 2-cyano-2-(pyrimidin-2-yl)acetateOn March 31, 1994, Oleinik, Irina V.; Zagulyaeva, Olga A. published an article in Mendeleev Communications. The article was 《Reaction of dihydroazinylidene cyanoacetic esters with nitric acid: a new method for the synthesis of dihydroazinylidene nitroacetonitriles》. The article mentions the following:

An approach to the synthesis of previously unknown dihydroazinylidene nitroacetonitriles (derivatives of pyridine, pyrimidine, pyrazine and pyridazine) has been developed involving nitration of the corresponding dihydroazinylidene cyanoacetic esters at the side chain α-C-atom and dealkoxycarbonylation of the resulting products. In the experimental materials used by the author, we found Ethyl 2-cyano-2-(pyrimidin-2-yl)acetate(cas: 65364-63-8Quality Control of Ethyl 2-cyano-2-(pyrimidin-2-yl)acetate)

Ethyl 2-cyano-2-(pyrimidin-2-yl)acetate(cas: 65364-63-8) is a member of pyrimidine. Pyrimidine derivatives are an important class of N-heterocycles. They are well-known for their wide spectrum of promising biological activities such as antitumors, bactericidals, and fungicidal.Quality Control of Ethyl 2-cyano-2-(pyrimidin-2-yl)acetate

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia