A new synthetic route of 110960-73-1

The synthetic route of 110960-73-1 has been constantly updated, and we look forward to future research findings.

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 110960-73-1, name is Ethyl 4-methylpyrimidine-5-carboxylate, the common compound, a new synthetic route is introduced below. Product Details of 110960-73-1

[229] Intermediate: 53: 4-methylpyrimidine-5-carboxylic acid: Intermediate 52 (2.6 g, 15.64 mmol) dissolved in sodium hydroxide solution (1.88 g, 47 mmol in 4 ml water) and refluxed. The reaction mixture was cooled to rt and acidified with con HCl to obtain the solid. Solid that obtained was filtered and dried to obtain the title compound (1.5 g) as an yellow solid. -NMR (delta ppm, DMSO-i , 400 MHz): 13.5 (bs, 1H), 9.14 (s, 1H), 9.05 (s, 1H), 2.71 (s, 3H).

The synthetic route of 110960-73-1 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; ICOZEN THERAPEUTICS PVT. LTD.; RHIZEN PHARMACEUTICALS S.A.; MUTHUPPALANIAPPAN, Peyyappan; VISWANADHA, Srikant; MERIKAPUDI, Gayatri, Swaroop; VAKKALANKA, Swaroop, Kumar, V.S.; WO2011/42797; (2011); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia