Category: 1073-65-0

Cohen, Sasson’s team published research in Journal of Medicinal Chemistry in 1971 | CAS: 1073-65-0

Pyrimidine-4-carbaldehyde oxime(cas: 1073-65-0) is a member of pyrimidine. Pyrimidine derivatives are an important class of N-heterocycles. They are well-known for their wide spectrum of promising biological activities such as antitumors, bactericidals, and fungicidal.COA of Formula: C5H5N3O

In 1971,Journal of Medicinal Chemistry included an article by Cohen, Sasson; Ashani, Yacov. COA of Formula: C5H5N3O. The article was titled 《Nucleophilicity of some reactivators of phosphorylated acetylcholinesterase. 5》. The information in the text is summarized as follows:

Reactivation of diisopropyl phosphorofluoridate-inactivated acetylcholinesterase by 14 heterocyclic oximes, was related with the nucleophilicity and basicity of these oximes. The value of kr (the 1st-order rate constant) at pH 7.4 was a function of both the nucleophilicity of the reactor mol., and its basicity, reaching an optimum for compounds with a pKa value in the range of 7.6-8.0, e.g., 1-methyl-4-formylrimidinium oxime iodide (I). The experimental process involved the reaction of Pyrimidine-4-carbaldehyde oxime(cas: 1073-65-0COA of Formula: C5H5N3O)

Pyrimidine-4-carbaldehyde oxime(cas: 1073-65-0) is a member of pyrimidine. Pyrimidine derivatives are an important class of N-heterocycles. They are well-known for their wide spectrum of promising biological activities such as antitumors, bactericidals, and fungicidal.COA of Formula: C5H5N3O

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Arnold, Zdzislaw’s team published research in Polish Journal of Chemistry in 1978 | CAS: 1073-65-0

Pyrimidine-4-carbaldehyde oxime(cas: 1073-65-0) is a member of pyrimidine. Pyrimidine derivatives are an important class of N-heterocycles. They are well-known for their wide spectrum of promising biological activities such as antitumors, bactericidals, and fungicidal.Related Products of 1073-65-0

Arnold, Zdzislaw; Draminski, Marcin; Fiszer, Bernard published an article in Polish Journal of Chemistry. The title of the article was 《Synthesis of quaternary pyrimidine bases, potential cholinesterase reactivators》.Related Products of 1073-65-0 The author mentioned the following in the article:

The title compounds I (R = Me, Et, Bu, X = I; R = Pr, allyl, X = Br) were obtained in 9-94% yields by quaternization of the oxime by RX in Me2CO 5-60 h at 37°. I showed no activity as cholinesterase reactivators. The results came from multiple reactions, including the reaction of Pyrimidine-4-carbaldehyde oxime(cas: 1073-65-0Related Products of 1073-65-0)

Pyrimidine-4-carbaldehyde oxime(cas: 1073-65-0) is a member of pyrimidine. Pyrimidine derivatives are an important class of N-heterocycles. They are well-known for their wide spectrum of promising biological activities such as antitumors, bactericidals, and fungicidal.Related Products of 1073-65-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia