Adding a certain compound to certain chemical reactions, such as: 3438-46-8, 4-Methylpyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Quality Control of 4-Methylpyrimidine, blongs to pyrimidines compound. Quality Control of 4-Methylpyrimidine
General procedure: Methyldiazine derivative (1mmol) and compound 3 (1.1equiv per methyl group) were dissolved in THF (20mL). tBuOK (1.5equiv per methyl group) was slowly added at room temperature. The solution, which immediately turned brown, was then refluxed overnight. After cooling, water was added, THF was evaporated and the mixture extracted with CH2Cl2, dried over MgSO4 and the solvent removed under vacuum.
The synthetic route of 3438-46-8 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Achelle, Sylvain; Kahlal, Samia; Saillard, Jean-Yves; Cabon, Nolwenn; Caro, Bertrand; Robin-Le Guen, Francoise; Tetrahedron; vol. 70; 17; (2014); p. 2804 – 2815;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia