The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 3680-69-1, name is 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine. This compound has unique chemical properties. The synthetic route is as follows. SDS of cas: 3680-69-1
38.4 g (250.4 mmol, 1.0 eq.) with stirring in an ice bath. 4-chloro-7H-pyrrole [2,3-d]pyrimidine is dissolved in 200 mL of dry DMF solution.13 g (305 mmol, 1.2 eq) of 57% NaH was added. The reaction was stirred at room temperature for 1 hour, then 50.9 g of SEMCl (305 mmol, 1.2 eq.).After the addition, the reaction was stirred in an ice bath for 1 hour. quenched with water, extracted with ethyl acetate. the title compound (71 g, yield = 100%) was obtained.
With the rapid development of chemical substances, we look forward to future research findings about 3680-69-1.
Reference:
Patent; Beijing Puqi Pharmaceutical Technology Co., Ltd.; Zhu Li; Hu Wei; Wang Jin; (32 pag.)CN109867675; (2019); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia