Adarve Garcia, E.; Escario, J.; Martinez Fernandez, A. R. published an article in 1982, the title of the article was Antitoxoplasmic effect of Lactotrim, sulfamethoxazole, and robenidine.Recommanded Product: 23256-42-0 And the article contains the following content:
The i.p. ED50 of Lactotrim (I) [23256-42-0] in mice infected with Toxoplasma gondii was 11 mg/kg. I.p. treatment with sulfamethoxazole (II) [723-46-6] (4-128 mg/kg) (alone was ineffective against the infection. Combined treatment with I and II (1:5; by weight) appeared synergistic, the ED50 being 8 mg/kg. robenidine [25875-51-8] Alone had an i.p. ED50 of 55 mg/kg; its 50% combination with I had an ED50 of 20 mg/kg. A combination of the 3 drugs (50% robenidine and 50% of the 1:5 mixture of I and II) had an ED50 of 18 mg/kg. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Recommanded Product: 23256-42-0
The Article related to antitoxoplasmic lactotrim sulfamethoxazole robenidine, Pharmacology: Effects Of Antimicrobials and Parasiticides and other aspects.Recommanded Product: 23256-42-0
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia