A new synthetic route of 101257-82-3

At the same time, in my other blogs, there are other synthetic methods of this type of compound,101257-82-3, 4-Amino-5-chloropyrimidine, and friends who are interested can also refer to it.

Application of 101257-82-3, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 101257-82-3, name is 4-Amino-5-chloropyrimidine. A new synthetic method of this compound is introduced below.

55. 2-({3-Chloro-2-[(5-chloro-pyrimidin-4-ylamino)-methyl]-pyridin-4-yl}-methyl-amino)-ethanol The compound is obtained analogously to Example 2 from 2-[(3-chloro-2-chloromethyl-pyridin-4-yl)-methyl-amino]-ethanol (4.7 g, 20 mmol) and 4-amino-5-chloro-pyrimidin (2.6 g, 20 mmol). Yield: 2.64 g (29%). Mp.: 158-161 C.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,101257-82-3, 4-Amino-5-chloropyrimidine, and friends who are interested can also refer to it.

Reference:
Patent; BYK Gulden Lomberg Chemische Fabrik GmbH; US6395732; (2002); B1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia