In 2018,European Journal of Organic Chemistry included an article by Bruening, Fabian; Katayev, Dmitry; Togni, Antonio. Synthetic Route of C4HCl3N2. The article was titled 《Facile and Efficient Synthesis of 3-Pyrimidinyl Oxindoles by Phase-Transfer-Catalyzed Regioselective Nucleophilic Aromatic Substitution》. The information in the text is summarized as follows:
Phase-transfer-catalyzed regioselective nucleophilic aromatic substitution of 2,4-dichloropyrimidines with N-Boc-protected 3-substituted oxindoles is reported. The reaction allows the formation of unsym. all- carbon quaternary centers in the benzylic position of heteroaromatic scaffolds and proceeds with high chem. yield and excellent functional-group tolerance. Various activated heteroaryl chlorides including dichloropyridazine and activated chloropyridines can also be reacted under the reaction conditions. The experimental part of the paper was very detailed, including the reaction process of 2,4,6-Trichloropyrimidine(cas: 3764-01-0Synthetic Route of C4HCl3N2)
2,4,6-Trichloropyrimidine(cas: 3764-01-0) is a member of organic chlorides. Organic chloride content in crude oil can be detected through specialized laboratory analysis. Care and attention are essential while sampling and testing.Synthetic Route of C4HCl3N2
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia