Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. One of the three diazines (six-membered heterocyclics with two nitrogen atoms in the ring), it has the nitrogen atoms at positions 1 and 3 in the ring. 4595-59-9, formula is C4H3BrN2, Name is 5-Bromopyrimidine. The pyrimidine ring system has wide occurrence in nature as substituted and ring fused compounds and derivatives, including the nucleotides cytosine, thymine and uracil, thiamine (vitamin B1) and alloxan. Computed Properties of 4595-59-9.
Dewan, Anindita;Sarmah, Manashi;Bhattacharjee, Prantika;Bharali, Pankaj;Thakur, Ashim J.;Bora, Utpal research published 《 Sustainable nano fibrillated cellulose supported in situ biogenic Pd nanoparticles as heterogeneous catalyst for C-C cross coupling reactions》, the research content is summarized as follows. This manuscript reports the design, synthesis and application of naturally occurring cellulose, generated from agro waste pomegranate peel, as novel support for active biogenic Pd (0) nanoparticles (NPs) for room temperature Suzuki-Miyaura and Sonogashira cross-coupling reactions. The presence of hydroxyl groups and unsaturated hanging bonds on their surfaces in cellulose matrix enable well dispersion of PdNPs over the support matrix to generate Pd@cellulose. This in turn exhibits excellent catalytic activity, easy removal from the reaction mixture, recyclable without loss of catalytic activity for Suzuki-Miyaura and Sonogashira reactions under ligand-free mild reaction conditions. The synthesized cellulosic nanofibers and Pd-anchored heterogeneous nanofibers were characterized by SEM, EDX, TEM, Powder XRD, FT-IR spectroscopy and BET surface anal.
Computed Properties of 4595-59-9, 5-Bromopyrimidine is a reactive intermediate that is used in the synthesis of 4-methoxyphenylboronic acid. 5-Bromopyrimidine has been shown to be nucleophilic, reacting with β-amino acids under basic conditions to form the corresponding 2-bromo amide. It also undergoes cross-coupling reactions with halides and can be used as a building block for other organic compounds. 5-Bromopyrimidine has optical properties that are characteristic of aromatic molecules, including strong absorption bands in the ultraviolet region and visible light region.
5-Bromopyrimidine undergoes direct metallation with lithuium diisopropylamide to yield 4-lithio-5-bromopyrimidine., 4595-59-9.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia