Electric Literature of 77994-12-8, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 77994-12-8, name is 2,5-Diaminopyrimidin-4(3H)-one. This compound has unique chemical properties. The synthetic route is as follows.
The water separator is arranged in the reaction vessel by adding the mass fraction of in 75percent cyclohexane 130 ml, phenyltheophylline methanol (3) 0.62mol, solid sodium sulfite 0.13mol, control the stirring speed 180rpm, raising the temperature of the solution 65 °C, heating 4h, the temperature of the solution is then reduced to 45 °C, by adding 2,5-diamino-pyrimidin-4-one (2) 0.73mol, continue to reflux reaction 6h, added after cooling the mass fraction of 15percent sodium chloride solution 300 ml, separating an aqueous layer, the organic layer used for quality score 65percent acetonitrile extraction, merged layer, 68kPa low-pressure distillation until the solution is clarified, reducing the temperature of the solution to 20 °C, by adding the mass fraction is 28percent oxalic acid solution is adjusted to pH 2, separating solid, filtering, in the mass fraction is 95percent nitromethane recrystallizing, to obtain crystal 2-benzyloxy-5-amino-pyrimidin-4-one 124.12g, yield 91percent.
According to the analysis of related databases, 77994-12-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Chengdu Science and Technology Co., Ltd. Chester; Peng, Fei; (5 pag.)CN105503740; (2016); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia