Related Products of 46155-89-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 46155-89-9, name is 1,3-Dimethyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione. This compound has unique chemical properties. The synthetic route is as follows.
Intermediate 3 1 ,3,7-Trimethyl- lH-pyrrolo[3,2-^]pyrimidine-2,4(3H,5H)-dioneCH3CH3Step 1 l,3-Dimethyl-2,4-dioxo-2,3,4,5-tetrahydro-l//-pyrrolo[3,2-c/]pyrimidine-7- carbaldehyde: At a temperature of 5-10C, phosphorous oxychloride (1.84 ml, 20.087 mmol) was mixed with iV.iV-dimethylformamide (2 mL). Then a solution of Intermediate 1 (600 mg, 3.348 mmol) in vV.jV-dimethylformamide (3 mL) was added while stirring. The reaction mixture was held for 2 h at 950C, cooled and poured onto ice (10 g). The precipitate formed was filtered off and recrystallised from water to give 300 mg of the product as an off-white solid; 1H NMR (delta ppm, 300 MHz, DMSO-^6) 3.25 (s, 3H), 3.75 (s, 3H), 8.06 (s, IH), 9.79 (s, IH), 13.15 (br s, IH); APCI-MS (m/z) 208.20 (M+H)+.
According to the analysis of related databases, 46155-89-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; GLENMARK PHARMACEUTICALS S.A.; CHAUDHARI, Sachin, Sundarlal; KUMAR, Sukeerthi; THOMAS, Abraham; PATIL, Nisha, Parag; KADAM, Ashok, Bhausaheb; DESHMUKH, Vishal, Govindrao; DHONE, Sachin Vasantrao; CHIKHALE, Rajendra, Prakash; KHAIRATKAR-JOSHI, Neelima; MUKHOPADHYAY, Indranil; WO2010/109287; (2010); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia