Related Products of 947533-45-1, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 947533-45-1, Name is 2-bromo-5-fluoropyrimidine, SMILES is FC1=CN=C(Br)N=C1, belongs to pyrimidines compound. In a article, author is Sivakrishna, Balija, introduce new discover of the category.
Design, synthesis and cytotoxic evaluation of truncated 3 ‘-deoxy-3 ‘, 3 ‘ difluororibofuranosyl pyrimidine nucleosides
Truncated 3′-deoxy- 3′, 3′ difluororibofuranosyl pyrimidine nucleoside derivatives were synthesized from D-ribose via beta-apioribo pyrimidine nucleoside intermediates 11a-c. The synthetic approach signifies that truncation at C3’ position of apioribose ring of 13a-c by oxidative cleavage of diols with Pb(OAc)(4) and followed by fluorination with DAST as key steps. Cytotoxic evaluation of synthesized truncated nucleoside derivatives 16a-c and 19a-c were tested against MCF7 and MDA-MB-231 breast cancer cell lines. However, only 19a was shown minimal growth suppression activity on MDA-MB-231 cancer cell lines.
Related Products of 947533-45-1, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 947533-45-1.
Reference:
Pyrimidine | C4H4N2 – PubChem,
,Pyrimidine – Wikipedia