Synthetic Route of 13316-12-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 13316-12-6, name is 7-Chlorothiazolo[5,4-d]pyrimidine. This compound has unique chemical properties. The synthetic route is as follows.
Example 11. 7-(2-indanylamino)thiazolo[5,4-d]pyrimidine Using 7-chlorothiazolo[5,4-d]pyrimidine (50 mg, 0.29 mmol) (see J. Org. Chem., 26, 4961 (1961), Chem. Pharm. Bull., 16, 750 (1968)) and 2-aminoindan (120 mg, 0.90 mmol), a similar procedure to Example 1 was carried out. The product obtained was purified by silica gel chromatography (hexane: ethyl acetate = 2: 1) to obtain the title compound (41 mg, 0.15 mmol) having the following physical properties: 1H NMR (400 MHz, CDCl3): delta 3.01 (2H, m), 3.50 (2H, m), 5.14 (1H, br.), 6.33 (1H, br.), 7.19-7.28 (4H, m), 8.56 (1H, s), 8.74 (1H, s), 8.49 (1H, s). MS (FAB): m/z 269 (M+H)+.
According to the analysis of related databases, 13316-12-6, the application of this compound in the production field has become more and more popular.
Reference:
Patent; SUNTORY LIMITED; EP1018514; (2000); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia