Schultes, Sabine published the artcileCombining Quantum Mechanical Ligand Conformation Analysis and Protein Modeling to Elucidate GPCR-Ligand Binding Modes, HPLC of Formula: 56-05-3, the publication is ChemMedChem (2013), 8(1), 49-53, database is CAplus and MEDLINE.
2-Aminopyrimidine ligands with flexible and rigid side chains was synthesized to investigate the role of ligand conformation in H4R ligand binding. The ligand binding conformations and orientations in the H4R binding pocket was elucidated. The combined ligand- and protein-ligand modeling method can be used as a general approach to investigate the binding modes of flexible side chains of ligands with other protein targets.
ChemMedChem published new progress about 56-05-3. 56-05-3 belongs to pyrimidines, auxiliary class Pyrimidine,Chloride,Amine,API, name is 2-Amino-4,6-dichloropyrimidine, and the molecular formula is C25H29N9O3, HPLC of Formula: 56-05-3.
Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/Pyrimidine,
Pyrimidine – Wikipedia