Alivizatos, A. S. published an article in 1987, the title of the article was Comparison of the antibiotic sensitivity in vitro of Spiroplasma kunkelii and Spiroplasma citri.Reference of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate And the article contains the following content:
The susceptibility of S. kunkelii (corn stunt spiroplasma, CSS) and S. citri to 17 antibiotics, was tested in vitro. The helical and nonhelical isolate of S. citri showed similar patterns of susceptibility to most antibiotics. However the helical isolate was more sensitive to trimethoprim (30 μg/mL) and more resistant to rhodomycin (10 μg/mL) and rifamycin (60 μg/mL) than the nonhelical isolate (180-240 μg/mL, 0.1-1 μg/mL, and 10-20 μg/mL resp.). S. kunkelii was more sensitive than S. citri to chlortetracycline-HCl (CSS 1.25 μg/mL, S. citri 10-15 μg/mL) and trimethoprim (CSS 5 μg/mL, S. citri 30 μg/mL for the helical isolate and 180-240 μg/mL for the nonhelical isolate), while its sensitivity to rhodomycin (10 μg/mL) and rifamycin (12.5 μg/mL) was similar to that of the helical and nonhelical isolate of S. citri, resp. The sensitivity of S. kunkelii to the other 13 antibiotics (erythromycin, tetracycline-HCl, chloramphenicol, kanamycin, streptomycin, neomycin, nalidixic acid, trimethoprim lactate, polymyxin-B, nystatin, thallium acetate, cycloheximide, penicillin-G) was similar to that of S. citri. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Reference of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate
The Article related to spiroplasma antibiotic susceptibility, Microbial Biochemistry: Antimicrobial Sensitivity and other aspects.Reference of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia