The nomenclature of pyrimidines is straightforward. However, like other heterocyclics, tautomeric hydroxyl groups yield complications since they exist primarily in the cyclic amide form. 4595-59-9, formula is C4H3BrN2, Name is 5-Bromopyrimidine. For example, 2-hydroxypyrimidine is more properly named 2-pyrimidone. A partial list of trivial names of various pyrimidines exists. Related Products of 4595-59-9.
Shcherbakov, Stanislav V.;Nadein, Oleg N.;Shcherbakova, Viktoriia Yu.;Ovcharov, Sergei N.;Aksenov, Alexander V. research published 《 Synthesis of Nonsymmetrically 2,7-disubstituted 1,3-diazapyrenes, Novel Promising Supramolecular Chemistry Objects》, the research content is summarized as follows. A number of nonsym. 2,7-disubstituted 1,3-diazapyrenes I (R1 = Ph, Bn, 3-HOC6H4, etc.; R2 = Ph, n-C5H11) were synthesized by the Sonogashira cross coupling of 2-substituted 7-bromobenzo[gh]perimidines with phenyl- and pentylacetylenes. A method of direct one-pot synthesis from 2-substituted 6-(5-bromo-3,4-dihydropyrimidin-4-yl)-1H-perimidines was developed. The proposed method for functionalization of 1,3-diazapyrenes can find application in supramol. chem.
Related Products of 4595-59-9, 5-Bromopyrimidine is a reactive intermediate that is used in the synthesis of 4-methoxyphenylboronic acid. 5-Bromopyrimidine has been shown to be nucleophilic, reacting with β-amino acids under basic conditions to form the corresponding 2-bromo amide. It also undergoes cross-coupling reactions with halides and can be used as a building block for other organic compounds. 5-Bromopyrimidine has optical properties that are characteristic of aromatic molecules, including strong absorption bands in the ultraviolet region and visible light region.
5-Bromopyrimidine undergoes direct metallation with lithuium diisopropylamide to yield 4-lithio-5-bromopyrimidine., 4595-59-9.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia