Month: April 2022

Category: pyrimidines. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 5-Methylfuran-2(3H)-one, is researched, Molecular C5H6O2, CAS is 591-12-8, about Nutritional value and volatiles of the edible mushroom Leucocalocybe mongolica. Author is Wang, X.; Bao, H.; Bau, T..

Leucocalocybe mongolica (S.Imai) X.D.Yu & Y.J.Yao is a rare edible wild mushroom that is highly regarded in northeast Asia. Owing to its desirable flavor and health attributes, L. mongolica is collected unscrupulously by indigenous peoples and mycophiles. In addition, its habitat is under constant threat from human activities, and the wild production continues to decline as it cannot keep pace with the rate of harvest. To date, no cultivation techniques that can produce L. mongolica have been discovered; however, utilizing fermentation technol. offers a promising alternative approach. In this study, the nutrients and volatile components of the products arising from two fermentation techniques were evaluated. Significant differences were observed between the fruiting bodies and the fermented products of L. mongolica with respect to protein, fat, and fiber contents. The results of gas chromatog.-mass spectrometry showed that 21 volatile components likely account for the flavor of basidiocarps. The two fermentation methods exhibited significant differences in terms of the enrichment of the different volatile compounds Comparison of the active components before and after solid-state fermentation on L. mongolica showed that the content of flavonoids, polysaccharides, triterpenoids, sterols, and phenols after solid-state fermentation was enhanced compared with the unleavened substrate. Given these results, solid-state fermentation technol. for L. mongolica appears to be a promising alternative to cultivation.

Compound(591-12-8)Category: pyrimidines received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5-Methylfuran-2(3H)-one), if you are interested, you can check out my other related articles.

Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Korodi, Ferenc published an article about the compound: 4-Chloro-8-methylquinoline( cas:18436-73-2,SMILESS:CC1=C2N=CC=C(Cl)C2=CC=C1 ).Quality Control of 4-Chloro-8-methylquinoline. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:18436-73-2) through the article.

Synthesis of 4-(1H-1,2,4-triazol-1-yl)quinolines by the reaction of 4-chloroquinolines with 1,2,4-triazole was studied under neutral, acidic and basic reaction conditions. The significant role of acid and base catalysis as well as substituent effects on the reactivity of 4-chloroquinolines in these reactions are reported.

Compound(18436-73-2)Quality Control of 4-Chloro-8-methylquinoline received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(4-Chloro-8-methylquinoline), if you are interested, you can check out my other related articles.

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Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 2-Bromo-3-methoxypropanoic acid, is researched, Molecular C4H7BrO3, CAS is 65090-78-0, about Tailored Synthesis of Skeletally Diverse Stemona Alkaloids through Chemoselective Dyotropic Rearrangements of β-Lactones, the main research direction is stemona alkaloid synthesis chemoselective dyotropic rearrangement lactone; alkaloids; dyotropic rearrangement; natural products; photoredox catalysis; total synthesis.Quality Control of 2-Bromo-3-methoxypropanoic acid.

The collective synthesis of skeletally diverse Stemona alkaloids featuring tailored dyotropic rearrangements of β-lactones as key elements is described. Specifically, three typical 5/7/5 tricyclic skeletons associated with stemoamide, tuberostemospiroline and parvistemonine were first accessed through chemoselective dyotropic rearrangements of β-lactones involving alkyl, hydrogen, and aryl migration, resp. By the rational manipulation of substrate structures and reaction conditions, these dyotropic rearrangements proceeded with excellent efficiency, good chemoselectivity and high stereospecificity. Furthermore, several polycyclic Stemona alkaloids, including saxorumamide, isosaxorumamide, stemonine and bisdehydroneostemoninine (I – IV, resp.), were obtained from the aforementioned tricyclic skeletons through late-stage derivatizations. A novel visible-light photoredox-catalyzed formal [3+2] cycloaddition was also developed, which offers a valuable tool for accessing oxaspirobutenolide and related scaffolds.

Compound(65090-78-0)Quality Control of 2-Bromo-3-methoxypropanoic acid received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(2-Bromo-3-methoxypropanoic acid), if you are interested, you can check out my other related articles.

Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 591-12-8, is researched, Molecular C5H6O2, about Trimetallic Cu-Ni-Zn/H-ZSM-5 Catalyst for the One-Pot Conversion of Levulinic Acid to High-Yield 1,4-Pentanediol under Mild Conditions in an Aqueous Medium, the main research direction is trimetallic copper nickel zinc hydrogen ZSM5 catalyst levulinate pentanediol.Electric Literature of C5H6O2.

The one-pot direct conversion of levulinic acid (LA) to 1,4-pentanediol (1,4-PDO) was investigated over a trimetallic Zn-promoted Cu-Ni alloy on a H-ZSM-5 (Cu-Ni-Zn/H-ZSM-5) catalyst. Under mild reaction conditions at 130°C and a H2 pressure of 2.5 MPa for 6 h in an aqueous medium, almost complete conversion of LA to high-yield 1,4-PDO (93.4%) was achieved. The presence of the Zn promoter effectively suppressed the growth of the Cu-Ni alloy nanoparticles (NPs) on the surface of H-ZSM-5. Consequently, the reducibility of the Cu-Ni-Zn alloy was much higher than that of the Cu-Ni alloy. The numerous Lewis acid sites of the Cu-Ni-Zn/H-ZSM-5 catalyst enhanced the adsorption of LA, and the adsorbed LA was converted to γ-valerolactone (GVL) at the Bronsted acid sites of H-ZSM-5 followed by hydrogenation at the Cu-Ni alloy sites. Subsequently, the readsorption of GVL was activated at the Lewis acid sites and GVL underwent ring opening, followed by hydrogenation to form 1,4-PDO at the Cu-Ni alloy sites. The H2 spillover on the Zn-promoted Cu-Ni alloy NPs enhanced the hydrogenation of LA to 1,4-PDO. Because of the mild reaction conditions, the formation of coke and active site sintering was highly suppressed. In addition, metal leaching did not occur over the trimetallic Cu-Ni-Zn/H-ZSM-5 catalyst. Consequently, the Cu-Ni-Zn/H-ZSM-5 catalyst could be used for up to five cycles with minimal activity loss.

Compound(591-12-8)Electric Literature of C5H6O2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5-Methylfuran-2(3H)-one), if you are interested, you can check out my other related articles.

Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《A novel BMSN (biologically synthesized mesoporous silica nanoparticles) material: synthesis using a bacteria-mediated biosurfactant and characterization》. Authors are Sharma, Raju Kumar; Wang, Shau-Chun; Maity, Jyoti Prakash; Banerjee, Pritam; Dey, Gobinda; Huang, Yi-Hsun; Bundschuh, Jochen; Hsiao, Ping-Gune; Chen, Tsung-Hsien; Chen, Chien-Yen.The article about the compound:5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloridecas:148-51-6,SMILESS:OC1=C(C)C(CO)=CN=C1C.[H]Cl).Application In Synthesis of 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride. Through the article, more information about this compound (cas:148-51-6) is conveyed.

Mesoporous materials (MMs) have recently been applied as advanced nanomaterials in different fields (separation, catalysis, adsorption etc.). Synthesis of MMs by chem. surfactants is not ecofriendly. This study focused on the biol. synthesis of a MM by sol-gel method, using a Bacillus subtilis BBK006-mediated surfactant (template) and a precursor (TEOS). The biol. synthesized mesoporous silica nanoparticles (BMSN) were formed at calcination temperatures of 450-600 °C. The BMSN comprise Si and O elements with sp. weights of 56.09% and 42.13% resp., where the at.% was detected to be 41.79% and 55.10%, resp. The phase identity of the synthesized particles (61-300 nm uniform spherical shape; surface area: 8.2616 m2 g-1; pore diameter at 550 °C: 14.8516 nm) was confirmed with wide-angle XRD (10°-81°). A typical type IV isotherm was exhibited (BET curves) following IUPAC nomenclature and confirmed the mesoporous nature. The green-synthesized biosurfactant-mediated BMSN is an environmentally promising material to apply in biomedical science (e.g., antimicrobial activity, drug delivery, CMC, anticancer activity) and oil spill management.

Compound(148-51-6)Application In Synthesis of 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride), if you are interested, you can check out my other related articles.

Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 148-51-6, is researched, Molecular C8H12ClNO2, about Preconvulsive changes in brain glucose metabolism following drugs inhibiting glutamate decarboxylase, the main research direction is convulsant brain glucose glycogen; allylglycine brain glucose glycogen; deoxypyridoxine brain glucose glycogen; methionine sulfoximine brain glucose; isoniazid brain glucose glycogen; temperature brain glucose convulsant.Application In Synthesis of 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride.

DL-C-allylglycine (I) [7685-44-1], 4-deoxypyridoxine-HCl (II) [148-51-6], and DL-methionine-D-sulfoximine (III) (180, 250, and 300 mg/kg resp., i.p.) each induced preconvulsive increases in the brain glucose [50-99-7] concentration of mice at room temperature; II and III also increased brain glycogen [9005-79-2] concentrations in room-temperature mice, but only II did so in mice maintained at 33-4°. Only with I was the increase in brain glucose concentration associated with an increase in blood glucose concentration I, II, III, or isoniazid [54-85-3] (150 mg/kg) reduced rectal temperature in mice at room temperature but not those at 33-4°. Isoniazid reduced brain glucose and glycogen concentrations in mice at 33-4°, but did not affect mice at room temperature The relation between the effects of these drugs on brain carbohydrates and amino acid metabolism is discussed.

Compound(148-51-6)Application In Synthesis of 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride), if you are interested, you can check out my other related articles.

Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Preparation of 3-hydroxy-5-hydroxymethyl-2,4-dimethylpyridine (4-deoxyadermine)》. Authors are Wibaut, J. P.; Uhlenbroek, J. H.; Kooijman, E. C.; Kettenes, D. K..The article about the compound:5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloridecas:148-51-6,SMILESS:OC1=C(C)C(CO)=CN=C1C.[H]Cl).Quality Control of 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride. Through the article, more information about this compound (cas:148-51-6) is conveyed.

The preparation of 4-deoxyadermine (I) as described earlier (CA 38, 32849) was improved to give a total yield 15%. Ac2CH2 (25 g.) was slowly added to a refluxing solution of 21 g. NCCH2CONH2 in 150 ml. EtOH and 3 ml. piperidine to give 97% 2-hydroxy-3-cyano-4,6-dimethylpyridine (II), m. 294°, which on nitration with HNO3 (d. 1.52) in Ac2O at 45-50° gave a 5-nitro derivative (III) m. 268° in 70% yield. A mixture of 50 g. dry III and 65 g. PCl5 was treated with 30 ml. POCl3 and heated to 130°, to yield 71% 2,4-dimethyl-3-nitro-5-cyano-6-chloropyridine, m. 112-13° (EtOH), which was reduced by Pd-C in MeOH and aqueous HCl to give 70-5% 2,4-dimethyl-3-amino 5-aminomethylpyridine di-HCl salt monohydrate (IV), m. 310° (decomposition). The reaction of IV with Ba(NO2)2 and H2SO4 at 0°, and subsequent heating to 90° afforded 45% I, m. 264°.

Compound(148-51-6)Quality Control of 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride), if you are interested, you can check out my other related articles.

Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 5-Methylfuran-2(3H)-one, is researched, Molecular C5H6O2, CAS is 591-12-8, about Cigar leaf differences from different producing areas based on aroma component analysis, the main research direction is cigar leaf aroma component.Electric Literature of C5H6O2.

In order to investigate the leaf aroma chem. differences for cigar samples from different producing areas, 79 aroma components in 47 cigar samples from different countries were determined In addition, the differences in contents and odor activity values of aroma components among Cuban cigars, foreign non-Cuban cigars and Chinese cigars were compared by significance tests. The results showed that there were significant differences in the contents of 43 aroma components among the cigars from different producing areas, and the differences in the contents of α-curcumene and cedrol were the most significant. The contents of degradation products from chlorophyll and cembranoids in Cuban cigars were higher, those of phenylalanines and labdanums in foreign non-Cuban cigars and that of chlorophyll in Chinese cigars were lower. The 79 aroma components had higher odor activity values in fruit and flower flavors. Cuban cigars had higher odor activity values in herbal spices, fruit, flower and other flavors. Foreign non-Cuban cigars had lower odor activity values in plant, fruit, nut, flower and other flavors. The discriminant functions established by taking the contents of aroma components as variables can distinguish the producing areas of com. cigars.

Compound(591-12-8)Electric Literature of C5H6O2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5-Methylfuran-2(3H)-one), if you are interested, you can check out my other related articles.

Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 148-51-6, is researched, SMILESS is OC1=C(C)C(CO)=CN=C1C.[H]Cl, Molecular C8H12ClNO2Journal, Pathologica called Effects of deoxpyridoxine on the formation and development of some experimental neoplasias. I. Ascites tumor in mice, Author is Grimaldi, T.; La Pesa, M.; Curci, E.; Semeraro, N., the main research direction is vitamin B6 antagonist tumor; cancer deoxypyridoxine; pyridoxine antagonist tumor.Synthetic Route of C8H12ClNO2.

I.p. or i.m. injection of the antivitamin B6 compound 4-deoxypyridoxine-HCl (I) [148-51-6] (0.07 mg/day) did not alter either the percentage of tumor take or the survival time of mice inoculated previously or subsequently with Ehrlich ascites tumor. The mice were not kept on a vitamin B6-deficient diet.

Compound(148-51-6)Synthetic Route of C8H12ClNO2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride), if you are interested, you can check out my other related articles.

Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 591-12-8, is researched, SMILESS is O=C1OC(C)=CC1, Molecular C5H6O2Journal, Journal of Catalysis called Investigation of solvent effects in the hydrodeoxygenation of levulinic acid to γ-valerolactone over Ru catalysts, Author is Mamun, Osman; Saleheen, Mohammad; Bond, Jesse Q.; Heyden, Andreas, the main research direction is levulinic acid hydrodeoxygenation valerolactone ruthenium catalyst solvent effect.Application In Synthesis of 5-Methylfuran-2(3H)-one.

Liquid phase, reductive deoxygenation of biomass derived platform chems. over transition metal surfaces constitutes an efficient scheme for upgrading lignocellulosic biomass. The solvation effects on the reaction kinetics of the hydrodeoxygenation (HDO) of levulinic acid (LA) towards the formation of γ-valerolactone (GVL) over Ru(0 0 0 1) has been studied in three condensed phase media, i.e., liquid water, methanol, and 1,4-dioxane. Detailed microkinetic models have been developed incorporating various catalytic pathways including formation of 4-hydroxypentanoic acid (HPA) and α-angelicalactone (AGL) to simulate the catalytic activity of Ru(0 0 0 1) under various reaction conditions of solvent, temperature, and partial pressures. Our microkinetic models suggest that direct catalytic conversion with alkoxy formation is the preferred reaction mechanism in all reaction environments. Furthermore, we find that water facilitates the reaction kinetics significantly and that the solvent effect is strongest at lower temperatures (T < 373 K). Here, rate increases due to liquid water solvation effects of 2-4 orders of magnitude are observed All solvents increase the rate of reaction relative to the gas phase; however, solvation effects decrease with decrease in polarity. 1,4-dioxane increases the rate only minimally due to competitive adsorption of the solvent mols. despite facilitating the partially rate controlling step of the LA hydrogenation to an alkoxy intermediate. Compound(591-12-8)Application In Synthesis of 5-Methylfuran-2(3H)-one received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5-Methylfuran-2(3H)-one), if you are interested, you can check out my other related articles.

Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia